| 100% | EDWINS | 6 | Astronomer Hubble and astronaut Aldrin |
| 39% | EDWIN | 5 | Astronomer Hubble |
| 38% | EDWINS | 6 | Hubble and Moses |
| 35% | EDWIN | 5 | First name of astronomer Hubble |
| 35% | ALANS | 5 | Actor Rickman and astronaut Shepard |
| 34% | CREWMATES | 9 | Aldrin, Armstrong and Collins |
| 33% | EILEENS | 7 | Astronaut Collins and others |
| 33% | NEILS | 5 | Astronaut Armstrong and others |
| 33% | GLENN | 5 | Astronaut and senator John |
| 33% | ALANS | 5 | Astronauts Bean and Shepard |
| 33% | JOB | 3 | Astronomer or astronaut, e.g. |
| 33% | NASA | 4 | Organization interested in spaceships and astronauts: Abbr. |
| 33% | EDWIN | 5 | Astronomer Hubble for whom the Hubble Space Telescope was named |
| 33% | CLYDES | 6 | Astronomer Tombaugh and aviator Cessna |
| 33% | SAGAN | 5 | Astronomer and extraterrestrial researcher Carl __ |
| 33% | ALDRIN | 6 | Astronaut with Armstrong and Collins |
| 31% | DOUG | 4 | Bob and ___ (NASA astronauts) |
| 31% | TELESCOPES | 10 | The Hubble and the upcoming James Web, for two |
| 31% | GHEZ | 4 | Astronomer and 2020 Nobel Prize winner Andrea |
| 31% | SAGAN | 5 | Astronomer Carl who wrote "Cosmos" and "Contact" |
| 31% | GALILEI | 7 | Galileo __, Italian astronomer and physicist |
| 31% | ISAAC | 5 | ___ Newton, English mathematician and astronomer |
| 31% | HYPATIA | 7 | Mathematician and astronomer from Alexandria |
| 31% | SAGAN | 5 | "Cosmos" writer and astronomer Carl |
| 31% | CARL | 4 | ___ Sagan, famous astronomer and astrophysicist |
| 31% | OMAR | 4 | Persian poet and astronomer Khayyám |
| 31% | SCOTT | 5 | Apollo 9 and 15 astronaut |
| 31% | GORDO | 5 | Mercury and Gemini astronaut, informally |
| 30% | LAPLACE | 7 | Marquis de ___ (French mathematician and astronomer) |
| 30% | HERSCHEL | 8 | German astronomer siblings William and Caroline |