| 100% | DAVIDMITCHELL | 13 | Author of the novel that was adapted into the 2012 film 7-/49-Across |
| 56% | NATIVESON | 9 | Best-selling 1940 novel that was adapted into a film, with its author playing the protagonist, in 1951 |
| 55% | BEES | 4 | "The Secret Life of ___," 2001 Sue Monk Kidd novel that was adapted into a 2008 film starring Queen Latifah |
| 54% | DENNISLEHANE | 12 | Author of the 2001 novel "Mystic River" that was made into a 2003 Sean Penn film: 2 wds. |
| 52% | BEAVER | 6 | "The Sign of the ___," 1983 Elizabeth George Speare novel that was adapted into the film "Keeping the Promise" |
| 51% | DOLPHINS | 8 | "Island of the Blue ___," 1960 Scott O'Dell novel that was adapted into a 1964 James B. Clark film |
| 50% | SALT | 4 | The Price of ___ (novel that was adapted into the movie Carol) |
| 50% | OLDMAN | 6 | *"The ___ and the Sea," 1952 novel by Ernest Hemingway that was adapted into a 1958 film: 2 wds. |
| 50% | NILE | 4 | "Death on the ___," 1937 novel by Agatha Christie that was adapted into the eponymous 2022 mystery film |
| 49% | LIANEMORIARTY | 13 | Author of the novel "Big Little Lies" which was adapted into an Emmy-winning TV series: 2 wds. |
| 49% | GOD | 3 | "Child of ___," 1973 novel by Cormac McCarthy that was adapted into a 2013 film |
| 48% | SHINING | 7 | "The ___ Girls," 2013 novel by Lauren Beukes that was adapted into 2022 TV series of the same name |
| 48% | SING | 4 | "Where the Crawdads ___," 2018 novel by Delia Owens that was adapted into an eponymous 2022 thriller film |
| 48% | ACT | 3 | "Sister ___," 1992 film starring Whoopi Goldberg that was adapted into a stage musical of the same name |
| 48% | VENDETTA | 8 | "V for ___," graphic novel by Alan Moore about a dystopian future in the UK that was adapted into a Natalie Portman film |
| 48% | LAURALIPPMAN | 12 | Author of the 2019 novel "Lady in the Lake," which was adapted into an Apple TV+ miniseries starring 19-Across and 34-Across (2 wds.) |
| 47% | INTERVIEW | 9 | "___ with the Vampire," 1976 gothic horror novel by Anne Rice that was adapted into a film starring Brad Pitt |
| 47% | ALIVE | 5 | "Luckiest Girl ___," 2015 novel by Jessica Knoll that was adapted into 2022 mystery thriller movie of the same name |
| 46% | ROAD | 4 | "The ___," 2006 novel by Cormac McCarthy that was adapted into a 2009 survival film |
| 46% | PAULAHAWKINS | 12 | Author of "The Girl on the Train," a novel adapted into a film starring Emily Blunt (2 wds.) |
| 46% | NAKEDSUN | 8 | "The ___," 1957 sci-fi novel by Isaac Asimov that was adapted into an episode of the TV series "Out of the Unknown": 2 wds. |
| 46% | STORYOFYOURLIFE | 15 | Ted Chiang novella that was adapted into the film "Arrival" |
| 46% | DAN | 3 | I wrote the Robert Langdon series and three of my novels were adapted into films |
| 45% | HIGHFIDELITY | 12 | 50-Across novel that was adapted into a feature film in 2000, a Broadway musical in 2006, and a TV series in 2020 (2 wds.) |
| 44% | DARK | 4 | "The ___ Knight Returns," graphic novel by Frank Miller that was adapted into a film trilogy starring Christian Bale as Batman |
| 44% | SCOTT | 5 | "___ Pilgrim," series of graphic novels by Bryan Lee O'Malley that was adapted into a film starring Michael Cera |
| 44% | FOX | 3 | "Fantastic Mr ___," 1970 Roald Dahl novel that was adapted into a 2009 Wes Anderson film |
| 44% | CARRIE | 6 | 1974 novel by Stephen King that was adapted into a 1976 film starring Sissy Spacek |
| 44% | CARLHIAASEN | 11 | "Squeeze Me" author who wrote the novel that 49-Across is based on (2 wds.) |
| 43% | PYGMALION | 9 | Play written in 1912 by George Bernard Shaw that was adapted into the film "My Fair Lady" |