| 100% | FAE | 3 | Baby who was the first infant subject of a xenotransplant procedure in 1984 |
| 43% | ROSEANNEBARR | 12 | 1990s sitcom star who was the subject of a Comedy Central Roast in 2012: 2 wds. |
| 42% | JAMESFRANCO | 11 | "The Interview" star who was the subject of a Comedy Central Roast in 2013: 2 wds. |
| 42% | DONALDTRUMP | 11 | "The Apprentice" host who was the subject of a Comedy Central Roast in 2011: 2 wds. |
| 41% | ANNPRESTON | 10 | American physician and activist who was the first female dean of a medical school in the world: 2 wds. |
| 41% | ANNEMURRAY | 10 | "You Needed Me" singer who was made a Companion of the Order of Canada in 1984: 2 wds. |
| 40% | MEL | 3 | Allen who was the first host of "This Week in Baseball" |
| 40% | HUCKLEBERRY | 11 | ___ Finn, a fictional character who first appeared in 51a and is a friend of the protagonist |
| 39% | KATE | 4 | Middleton who was the subject of a disappearance conspiracy |
| 39% | LISALESLIE | 10 | Basketball Hall of Fame inductee who was the first player to dunk in a WNBA game: 2 wds. |
| 39% | MEANY | 5 | George who was the first president of the A.F.L.-C.I.O. |
| 39% | DIAMONDJIMBRADY | 15 | Tycoon who was the first person in New York City to own a car |
| 39% | REBA | 4 | McEntire who is the first woman to portray Colonel Sanders in a KFC ad |
| 39% | DIANA | 5 | Princess who was the subject of "Candle in the Wind" |
| 39% | SAMUELALITO | 11 | Nominee who was the subject of a 2006 filibuster attempt |
| 39% | ALTHEA | 6 | Gibson who was the first person of color to win a tennis Grand Slam event |
| 38% | ANDERSEN | 8 | Classic author who was the subject of a 1952 film musical |
| 38% | GERTRUDESTEIN | 13 | Pittsburgh-born poet who was the subject of a Picasso portrait |
| 38% | PAMELA | 6 | Actress Anderson who was the subject of a 2023 Netflix documentary |
| 38% | NYAD | 4 | Swimmer Diana who was the subject of a 2023 bio-pic |
| 38% | RETRACENACIRRUH | 15 | Exonerated boxer who is the subject of a Bob Dylan song |
| 38% | ALEC | 4 | Baldwin who was the first performer on screen in the current season of "Saturday Night Live" |
| 38% | MARTHA | 6 | Little ___, rabbit who was the first of her kind to be launched into space in 1959 |
| 38% | MEANY | 5 | Labor leader George who was the first president of the A.F.L.-C.I.O. |
| 38% | ALTHEAGIBSON | 12 | Tennis great who was the first person of color to win a Wimbledon championship (2 wds.) |
| 38% | SHIELDS | 7 | Actress Brooke who is the subject of the 2023 documentary "Pretty Baby" |
| 38% | ALI | 3 | Boxer who was the subject of a recent commemorative issue of Time |
| 38% | UMA | 3 | Actress Thurman who was the subject of a Fall Out Boy song |
| 38% | JUSTICEGINSBURG | 15 | Subject of this puzzle, who once said "Fight for the things that you care about, but do it in a way that will lead others to join you" |
| 38% | RETTON | 6 | Gymnast Mary Lou who was the first woman to appear on the front of a Wheaties box |