| 100% | ANAEROBE | 8 | Bacterium that doesn't need oxygen |
| 64% | AEROBE | 6 | Bacterium that needs oxygen |
| 64% | AEROBES | 7 | Bacteria that need oxygen |
| 56% | ANAEROBE | 8 | Organism that doesn't require oxygen |
| 56% | TESLA | 5 | Car that doesn't need gas |
| 56% | ECARD | 5 | Greeting that doesn't need postage |
| 56% | EMAIL | 5 | Correspondence that doesn't need stamps |
| 56% | MAC | 3 | Computer that doesn't need Windows |
| 56% | AXIOM | 5 | Statement that doesn’t need to be proven |
| 56% | FLOATPLANE | 10 | Aircraft that doesn't need a runway |
| 56% | ORAL | 4 | Test that doesn't need a pen |
| 55% | CLIPON | 6 | Tie that doesn't need to be tied |
| 55% | SHORTHAIR | 9 | Pet that doesn't need much brushing, say |
| 54% | CACTUS | 6 | Plant that doesn't need a lot of water |
| 54% | EMAIL | 5 | Letter that doesn't need an envelope or stamp |
| 53% | AIRPLANT | 8 | Nursery purchase that doesn't need to be watered |
| 53% | STATETHEOBVIOUS | 15 | *Say something that doesn't need to be said |
| 52% | SUCCULENT | 9 | Trendy plant that doesn't need a lot of water |
| 52% | GRANT | 5 | Financial aid that doesn't need to be paid back |
| 50% | SOFTSHOE | 8 | Type of tap dancing that doesn't need special footwear |
| 50% | SUCCULENT | 9 | Thick-leaved plant that doesn't need much water |
| 50% | PELLGRANT | 9 | Financial aid for college that doesn't need to be repaid |
| 45% | STOL | 4 | Abbr. for a plane that doesn't require much runway (but needs plenty of space if it goes backwards!) |
| 44% | POSTCARD | 8 | Mail that doesn't need an envelope, and where both words of 12-, 20-, 34-, and 51-Across can be found? |
| 43% | HAS | 3 | Doesn't need |
| 43% | WEAR | 4 | Wash-and-___ (like fabric that doesn't need dry cleaning) |
| 43% | AEROBES | 7 | Organisms that need oxygen |
| 43% | AEROBE | 6 | Organism that needs oxygen |
| 43% | ISOK | 4 | Doesn't need assistance |
| 42% | TASTESOK | 8 | Doesn't need more seasoning |