| 100% | RADIOHEAD | 9 | Band that performed “Creep” as the first-ever musical guest on “Late Night with Conan O’Brien” |
| 37% | IMAGINE | 7 | ___ Dragons, band that performed a song along with 8a which was featured on the "Suicide Squad" soundtrack album |
| 37% | METALLICA | 9 | Heavy metal band that performed with Lady Gaga on their song "Moth Into Flame" at the 2017 Grammys |
| 32% | MURRAY | 6 | Bill ___, "Kingpin" actor and comedian who was the first guest on the "Late Show with David Letterman" in 1993 |
| 32% | JOEL | 4 | Billy ___, "Uptown Girl" singer who was the first musical act on the "Late Show with David Letterman" in 1993 |
| 31% | SNL | 3 | Show on which Lizzo was the first woman to introduce herself as the musical guest (Abbr.) |
| 31% | BUGGLES | 7 | Band with the first video on MTV, with "the" |
| 30% | ABBA | 4 | Swedish pop band that has the first letter of each member on its name |
| 30% | OBAMA | 5 | President with the same first and last name as his father |
| 29% | MAYARUDOLPH | 11 | "Up All Night" actress who performed with the band The Rentals: 2 wds. |
| 29% | RENT | 4 | 1996 Broadway musical that opens with the words "We begin on Christmas Eve ..." |
| 29% | BEA | 3 | Flyer that performed the world's first automatic landing on a commercial flight on June 10, 1965 (abbr.) |
| 29% | ATSEVENTEEN | 11 | Song performed on the first episode of "Saturday Night Live" |
| 29% | ALLSTARGAME | 11 | Event known as the Midsummer Classic that first took place at Comiskey Park on July 6, 1933 (2 wds.) |
| 28% | TOTO | 4 | Band that performed "Hold the Line" and "Africa" |
| 28% | BASTILLE | 8 | Band with the album "Bad Blood" that was a first-time Grammy nominee for Best New Artist |
| 28% | NATE | 4 | ___ Dogg, the late rapper who collaborated several times with Eminem, most notably on "Shake That" |
| 28% | NHL | 3 | The first of these was declared on October 9, 1960 and the latest - Medgar Evers House - was on February 16, 2017 (abbr.) |
| 28% | QUESTLOVE | 9 | The Roots' frontman on "Late Night with Jimmy Fallon" |
| 28% | ANDY | 4 | Conan O'Brien's late-night sidekick Richter |
| 28% | DAVIDLETTERMAN | 14 | Former "Late Show" host who presented Conan O'Brien with the 2025 Twain Prize: 2 wds. |
| 27% | BEATLES | 7 | Rock band that memorably played Carnegie Hall on 2/12/1964, with "the" |
| 27% | ABBA | 4 | Band that inspired the musical "Mamma Mia!" |
| 27% | ARIANAGRANDE | 12 | "Thank U Next" singer who sings "Met Him Last Night" with Demi Lovato on "Dancing with the Devil ... the Art of Starting Over" (2 wds.) |
| 27% | NSYNC | 5 | Band with the song "Bye Bye Bye" whose name is an acronym of the last letters of the members' first names |
| 27% | SHANANA | 7 | Doo-wop rock band that performed in the movie "Grease" |
| 27% | LOLITA | 6 | 1955 novel with the line "It was love at first sight, at last sight, at ever and ever sight" |
| 27% | MILEYCYRUS | 10 | She played a character with the same first name (and the last name Stewart) on "Hannah Montana": 2 wds. |
| 27% | ABBIJACOBSON | 12 | She played a character with the same first name (and the last name Abrams) on "Broad City": 2 wds. |