| 100% | CLONE | 5 | Biological duplicate that is the subject of many sci-fi movies |
| 45% | VERTIGO | 7 | 1958 film that is the subject of this puzzle |
| 45% | EMU | 3 | Bird that was the subject of an Australian war |
| 45% | CIA | 3 | Grp. that was the subject of a recent WikiLeaks release |
| 45% | XIII | 4 | Apollo mission that was the subject of a 1995 film |
| 44% | GTO | 3 | Car that was the subject of a 1964 top 10 hit |
| 44% | AOL | 3 | Tech company that was the subject of a 1997 Time cover |
| 44% | TOLEDO | 6 | Spanish city that was the subject of an El Greco painting |
| 44% | ANGORAS | 7 | Wool sources that were the subject of a 2013 PETA exposé |
| 44% | EMI | 3 | Co. that was the subject of a Sex Pistols diss track |
| 44% | WVA | 3 | American state that is the subject of the song "Country Roads": Abbr. |
| 44% | ICBM | 4 | Long-range nuke that was the subject of the SALT treaty: Abbr. |
| 44% | KATRINA | 7 | Hurricane that was the subject of 2006's "When the Levees Broke" |
| 44% | AFRICA | 6 | Continent with Nigeria that is the subject of a song by Toto |
| 44% | FYRE | 4 | Failed music festival that was the subject of two popular 2019 documentaries |
| 44% | NCAA | 4 | Org. that was the subject of a 2021 Supreme Court antitrust ruling |
| 44% | NBA | 3 | League that was the subject of the docuseries “Shut Up and Dribble”: Abbr. |
| 43% | SASHA | 5 | ___ Fierce, Beyonce's onstage alter-ego that was the subject of her 2008 album |
| 43% | MALARIA | 7 | Disease that was the subject of the second Nobel Prize in Physiology or Medicine (1902) |
| 42% | POE | 3 | Author who was the subject of the 2012 movie "The Raven" |
| 42% | JAKE | 4 | Boxer LaMotta who was the subject of the movie "Raging Bull" |
| 42% | HERBALIFE | 9 | Controversial multilevel-marketing supplement company that was the subject of the 2016 documentary Betting on Zero |
| 42% | OTT | 3 | Fred whose sneeze is the subject of the oldest surviving copyrighted movie |
| 42% | DEAD | 4 | With 8-Across, subject of a theory that claims that most of the activity on social media is generated by bots |
| 42% | CHE | 3 | Revolutionary Guevara who was the subject of the movie "The Motorcycle Diaries" |
| 42% | SUNFLOWER | 9 | (See 12a) Bloom with edible seeds that was the subject of a famous painting by Van Gogh |
| 41% | DST | 3 | Observance that was the subject of a Last Week Tonight "How Is This Still a Thing?" segment: abbr. |
| 41% | BIEBER | 6 | Singer who was the subject of the 3-D concert movie Never Say Never |
| 41% | ELSA | 4 | Lion that was the subject of the book "Born Free" and that is buried in Kenya's Meru National Park |
| 40% | OPEC | 4 | Subject of the Atlantic article "The Cartel That Never Was" |