| 100% | SPOOL | 5 | Bobbin provides second game |
| 48% | RETURNMATCH | 11 | Second game |
| 46% | NIGHTCAP | 8 | Second game of doubleheader |
| 43% | NIGHTCAP | 8 | Second game of a baseball doubleheader, informally |
| 41% | SON | 3 | inFAMOUS: Second ___ (video game) |
| 41% | RETURNMATCH | 11 | Game's second leg |
| 40% | CATCHING | 8 | Second Hunger Games book: __ Fire |
| 39% | ALAI | 4 | Second half of a court game |
| 38% | TEAMB | 5 | Second side in a game (2 wds.) |
| 38% | TORSO | 5 | Second miss in a hangman game, often |
| 38% | DOUBLEJEOPARDY | 14 | Second round of a TV game show |
| 38% | SEEK | 4 | Second half of a children's game |
| 38% | JONGG | 5 | Second part of a Chinese game name |
| 37% | MINECRAFT | 9 | Second biggest selling video game (as of 2017) |
| 37% | MINECRAFT | 9 | Second-best-selling video game of all time |
| 36% | KNOWLEDGE | 9 | 30 Seconds is a general __ game |
| 36% | ACE | 3 | Second-highest-ranking card in the game pusoy dos |
| 36% | ASIAN | 5 | ___ Games, second-largest multisport event after the Olympics |
| 34% | ALAI | 4 | Second word of a game name that rhymes with the first |
| 32% | GTAV | 4 | The second-best-selling video game of all time, briefly |
| 32% | NIGHTCAP | 8 | *Second game of a doubleheader |
| 32% | WITHTHEWRENCH | 13 | Second part of a possible solution in a game of Clue (3 wds.) |
| 31% | MINECRAFT | 9 | After Tetris, the second-best-selling video game of all time |
| 31% | IAN | 3 | Retired second-baseman Kinsler who played in four All-Star games |
| 30% | KOBE | 4 | He scored the second-most points in a game in NBA history |
| 29% | BENZOBRIST | 10 | Cubs second baseman who started the 2016 MLB All-Star Game: 2 wds. |
| 29% | TOKYO | 5 | First Asian city scheduled to hold the Olympic Games for a second time |
| 27% | ROBINSONCANO | 12 | Seattle Mariners second baseman who won the 2017 MLB All-Star Game MVP: 2 wds. |
| 27% | PHILIPRIVERS | 12 | Chargers/Colts player who's started 224 consecutive games, second among all quarterbacks: 2 wds. |
| 27% | NOOB | 4 | Gamer who lacks game |