| 100% | LEON | 4 | Boxer Spinks who defeated 50-Down in 1978 |
| 79% | LEON | 4 | Boxer Spinks who defeated Muhammad Ali in 1978 |
| 59% | ALI | 3 | Boxer Muhammad who beat 26-Down Spinks in a 1978 rematch |
| 54% | ALI | 3 | Boxer who defeated Superman in a 1978 DC Comics issue |
| 40% | LEON | 4 | Boxer Spinks who upset Muhammad Ali |
| 39% | OSCARDELAHOYA | 13 | American boxer who was defeated by Floyd Mayweather Jr. in 2007: 4 wds. |
| 39% | MANNYPACQUIAO | 13 | Filipino boxer who was defeated by Floyd Mayweather Jr. in 2015: 2 wds. |
| 39% | CONORMCGREGOR | 13 | Irish boxer who was defeated by Floyd Mayweather Jr. in 2017: 2 wds. |
| 39% | MIKE | 4 | ___ Tyson, legendary boxer who Evander Holyfield defeated for the WBA title in 1996 |
| 38% | MUHAMMADALI | 11 | Boxer who defeated 43-Across in the 1974 bout billed as "The Rumble in the Jungle" (2 wds.) |
| 37% | BUSTERDOUGLAS | 13 | Boxer who scored a huge upset in 1990 when he defeated Mike Tyson for the heavyweight title: 2 wds. |
| 37% | LOSE | 4 | Go down in defeat |
| 37% | LOSING | 6 | Going down in defeat |
| 37% | LOSES | 5 | Goes down in defeat |
| 36% | LAILA | 5 | With 63-Down, boxer who retired undefeated in 2007 |
| 36% | ALI | 3 | Spinks defeater, 1978 |
| 35% | BOWE | 4 | Boxer who defeated Holyfield twice |
| 35% | BARBARA | 7 | Boxer who retired in 2017 |
| 34% | HOLLANDE | 8 | President who defeated Sarkozy in 2012 French vote |
| 34% | KEN | 3 | Boxer Norton who once defeated Ali |
| 34% | ALI | 3 | Boxer Muhammad who died in 2016 |
| 34% | TYSON | 5 | Boxer who appeared in "The Hangover" |
| 34% | LAILA | 5 | Boxer Ali who retired in 2007 |
| 34% | JOEPALOOKA | 10 | Boxer in strips for 50+ years |
| 34% | BRAD | 4 | With 50-Down, actor who plays an astronaut seeking his lost father in 8-Down |
| 34% | RUSSELLCROWE | 12 | "Gladiator" actor who plays boxer James J. Braddock in 5-Down (2 wds.) |
| 34% | ARA | 3 | Coach who defeated Bear in the 1973 Sugar Bowl |
| 33% | TYSON | 5 | Boxer Mike who appeared in "The Hangover" |
| 33% | ANN | 3 | Boxer Wolfe who appeared in "Wonder Woman" |
| 33% | FINNEY | 6 | "Erin Brockovich" star Albert who turned down the title role in 15-/50-Across |