| 100% | JAMESBOND | 9 | British spy played by many actors, including 46-Across (2 wds.) |
| 54% | JOHNNYENGLISH | 13 | Inept British spy played by 49-Across in three films (2 wds.) |
| 53% | JAMESBOND | 9 | British spy played by 33-Across for the first time in 48-Across (2 wds.) |
| 53% | JOHNNYENGLISH | 13 | Inept British spy played by 15-Across who "Strikes Again" in 2018 (2 wds.) |
| 52% | JAMESBOND | 9 | British spy played by 31-Across in 1969's "On Her Majesty's Secret Service" (2 wds.) |
| 45% | RAFESADLER | 10 | Character played by actor Thomas Brodie-Sangster in the British television serial "Wolf Hall" based on Hilary Mantel novels: 2 wds. |
| 44% | JOHNSTEED | 9 | Spy played by Patrick Macnee on "The Avengers": 2 wds. |
| 44% | JIMPHELPS | 9 | Spy played by Peter Graves on "Mission: Impossible": 2 wds. |
| 43% | ETHANHUNT | 9 | Fictional spy played by Tom Cruise in "Mission: Impossible" film series: 2 wds. |
| 42% | MARTINBYRDE | 11 | Financial analyst played by 46-Across on 40-Down (2 wds.) |
| 42% | NAPOLEONSOLO | 12 | Spy played by Robert Vaughn on "The Man From U.N.C.L.E.": 2 wds. |
| 42% | PRINCESSDIANA | 13 | British royal played by Emma Corrin on "The Crown" in 2020: 2 wds. |
| 42% | QUEENELIZABETH | 14 | British royal played by Olivia Colman on "The Crown" in 2020: 2 wds. |
| 40% | CHARLIEHUNNAM | 13 | Actor who plays 30-Across on 46-Across (2 wds.) |
| 40% | PRINCECHARLES | 13 | British royal played by Josh O'Connor on Netflix's "The Crown" in 2020: 2 wds. |
| 40% | HEATHERLEE | 10 | Character played by Alicia Vikander in the action spy movie "Jason Bourne": 2 wds. |
| 39% | CHRISTIANKANE | 13 | "Leverage" actor who plays Jacob Stone in 46-Across (2 wds.) |
| 39% | KEVINALEJANDRO | 14 | "Lucifer" actor who plays Manny Perez on 46-Across (2 wds.) |
| 39% | TARONEGERTON | 12 | "Rocketman" actor who plays James Keene in 46-Across (2 wds.) |
| 39% | CENTURYCYCLE | 12 | Series of 10 plays by 14-Across, including "Fences" and "The Piano Lesson," that chronicle life in Black America over a 100-year span: 2 wds. |
| 38% | MICHAELMYERS | 12 | Masked slasher who has been played by 16 different actors, including James Jude Courtney in 44-Across (2 wds.) |
| 38% | HARRYCALLAHAN | 13 | Police inspector played by 15-Across in "Sudden Impact": 2 wds. |
| 38% | WILLYWONKA | 10 | Chocolate factory owner played by 18-Across in 1971: 2 wds. |
| 38% | WHITEYWINN | 10 | Character played by actor Thomas Brodie-Sangster in the hit Netflix television drama mini-series "Godless": 2 wds. |
| 38% | SUESTORM | 8 | "Invisible Woman" played by Kate Mara in 31-Across: 2 wds. |
| 38% | BENGRIMM | 8 | "The Thing" played by Jamie Bell in 31-Across: 2 wds. |
| 38% | VINCENTVANGOGH | 14 | Painter played by 46-Across in 19-Across: 3 wds. |
| 38% | UNCLEJESSE | 10 | Role played by 18-Across on "Full House": 2 wds. |
| 37% | CHRISTIANKANE | 13 | "Leverage: Redemption" actor who played Jacob Stone on 46-Across (2 wds.) |
| 37% | MAXTHIERIOT | 11 | "SEAL Team" actor who plays Bode Donovan on 46-Across (2 wds.) |