| 100% | THROWACURVEBALL | 15 | Candy Cummings was the first pitcher to do this |
| 53% | PUT | 3 | Competitions to do this to the shot were first recorded in early 19th century Scotland |
| 47% | BLAZEATRAIL | 11 | Be the first to accomplish something (and do it spectacularly!) |
| 47% | NORTHPOLE | 9 | Robert Peary was the first to reach this place |
| 47% | TOBACCO | 7 | Rolfe was the first to cultivate this in Virginia |
| 46% | THOUSAND | 8 | This is the first number to have the letter "A" |
| 45% | MADAMSPEAKER | 12 | *Nancy Pelosi was the first person ever to have this title in Congress |
| 45% | SPORTSCENTER | 12 | Ronda Rousey was the first female athlete to guest-host this ESPN show |
| 45% | NONET | 5 | A chamber work by Louis Spohr was the first to bear this title |
| 44% | TOSSACOIN | 9 | Referees do this to decide who gets the ball first |
| 44% | ESPYAWARD | 9 | Ronda Rousey is the first mixed martial artist to win this athletic honor: 2 wds. |
| 43% | DOG | 3 | President Trump is the first president in over 100 years not to have one of these |
| 42% | ACADEMYAWARDS | 13 | 18-Across and 42-Across were the first Spanish actress and actor to win these honors: 2 wds. |
| 42% | USN | 3 | JFK was the first president to have served in this branch of the US Armed Forces |
| 42% | TIEATIE | 7 | The way to do this is the #1 how-to search, according to Google |
| 41% | JET | 3 | The Lippisch Ente was the first one of these to fly, in 1928 |
| 41% | RADIO | 5 | In 1922, Warren G. Harding became the first U.S. president to be broadcast over this |
| 41% | ERR | 3 | To do this is human |
| 41% | COIN | 4 | Be the first to use |
| 41% | COIN | 4 | Be the first to say |
| 41% | WIN | 3 | Be the first to finish |
| 41% | DISCOVER | 8 | Be the first to find |
| 40% | CPR | 3 | First-aid procedure that can be done to the beat of "360" by Charlie XCX |
| 40% | SPECULATE | 9 | It can be risky to do this in the stock market |
| 40% | COMINGINHOT | 11 | Arriving with great speed, and what the first words of the answers to the starred clues are doing? |
| 40% | WAYNEGRETZKY | 12 | Hockey legend who was the first since Bobby Orr to tally 100+ assists in a season, and did so 11 times: 2 wds. |
| 40% | ERR | 3 | To do this is human, it is said |
| 39% | WON | 3 | Was the first to cross the finish line |
| 39% | ERR | 3 | To do this is human, it's said |
| 39% | LEADOFF | 7 | Be the first baseball player to bat: 2 wds. |