| 100% | GTO | 3 | Car co-created and named by John DeLorean |
| 44% | JAM | 3 | 2000 Channel 4 comedy sketch show created and co-written by Chris Morris |
| 44% | GTO | 3 | 1960s muscle car designed by John Delorean |
| 40% | NUFFIELD | 8 | Lord —, name adopted by philanthropist and motor car manufacturer William Morris on being ennobled |
| 40% | MEN | 3 | Of Mice and ___, "Restoring Force" band whose name is inspired by a John Steinbeck novel |
| 39% | POLONIUM | 8 | Element discovered and named by Marie Curie |
| 39% | OREO | 4 | Treat whose name can be formed by concatenating a Cirque du Soleil show and a car |
| 39% | AMC | 3 | Car co. purchased by Chrysler |
| 39% | AMC | 3 | Car co. bought by Chrysler |
| 37% | ALEXANDER | 9 | I created one of the largest empires of the ancient world and my name is followed by "The Great" |
| 36% | TARS | 4 | Street car co. in Manhattan, the Bronx and lower Westchester County from 1852 until it was bought by the NYC Omnibus Corp. in '56 (abbr.) |
| 36% | VISION | 6 | Superhero co-created by 41-Across and played by Paul Bettany |
| 36% | FALCON | 6 | Superhero co-created by 41-Across and played by Anthony Mackie |
| 36% | TWOVIRGINS | 10 | 1968 album by John Lennon and Yoko Ono |
| 36% | DRUMS | 5 | Instrument played by John Bonham and Keith Moon |
| 36% | IMAGINE | 7 | Song written by John Lennon and Yoko Ono |
| 36% | XXXXXXXXXXXXXX | 14 | Booze pitched by John Legend and Chelsea Handler |
| 35% | EGOT | 4 | Accomplishment by John Legend, Viola Davis and Elton John |
| 35% | ONO | 3 | Plastic ___ Band (music group formed by John and Yoko) |
| 35% | TBIRD | 5 | Car driven by Thelma and Louise, familiarly |
| 35% | GEORGE | 6 | Name shared by presidents Bush and Washington |
| 35% | REPOS | 5 | Deadbeats' cars, by and by |
| 35% | DOCTORSTRANGE | 13 | Superhero co-created by 41-Across and played by Benedict Cumberbatch (2 wds.) |
| 35% | STENNIS | 7 | Former U.S. senator John C. ___, whose name can be formed by combining 44 Down and 22 Across and reversing the whole thing |
| 34% | ILLUMINATA | 10 | 1998 romcom featuring, directed and co-written by John Turturro |
| 34% | EMMYS | 5 | Awards won this week by John Mulaney and Bill Hader |
| 34% | CRASH | 5 | ___ Course, educational YouTube channel started by John and Hank Green |
| 34% | HYBRIDVEHICLES | 14 | Cars suggested by 20-, 26- and 48-Across? |
| 34% | THALIA | 6 | Name shared by a Grace and a Muse |
| 34% | TEAL | 4 | Name shared by a color and a duck |