| 100% | BERNSTEIN | 9 | Carl __, reporter played by Dustin Hoffman on film |
| 49% | MUMBLES | 7 | Dick Tracy villain played by Dustin Hoffman |
| 48% | BABBITT | 7 | Raymond, played by Dustin Hoffman in Rain Man |
| 48% | RAYMOND | 7 | Autistic savant played by Dustin Hoffman in 15-Across |
| 45% | LENNYBRUCE | 10 | Real-life comic played in film by Dustin Hoffman |
| 44% | LOIS | 4 | Title reporter played by Elizabeth on a 2020s CW series |
| 43% | CLEOPATRA | 9 | Foxxy __, character played by Beyonce on film |
| 42% | WAGTHEDOG | 9 | 1997 film in which Dustin Hoffman plays a producer working on a fake war: 3 wds. |
| 41% | BLACKJACK | 9 | Card game played by Tom Cruise and Dustin Hoffman in "Rainman" |
| 40% | ROMEO | 5 | Role played by Leonardo DiCaprio on film and Orlando Bloom on stage |
| 40% | EVITA | 5 | Musical role played by Madonna on film and Patti LuPone on Broadway |
| 38% | TOOTSIE | 7 | Classic film where Dustin Hoffman plays Dorothy |
| 38% | ELCID | 5 | Spanish hero played on film by Charlton Heston |
| 38% | DOLITTLE | 8 | John ___, fictional doctor played by Eddie Murphy in the 1998 film based on Hugh Lofting's stories |
| 37% | LENNY | 5 | Comedian played by Dustin |
| 37% | JONATHAN | 8 | Role played by Boris Karloff on Broadway and Raymond Massey in the film |
| 37% | RAINMAN | 7 | Dustin Hoffman film |
| 37% | HERO | 4 | Dustin Hoffman film |
| 36% | LOISLANE | 8 | Reporter played by Amy Adams in "Justice League" |
| 36% | LOISLANE | 8 | Reporter played by Rachel Brosnahan in "Superman" (2 wds.) |
| 36% | THEGRADUATE | 11 | Dustin Hoffman's breakthrough film |
| 35% | VENICE | 6 | "The Merchant of ___," 1969 short film directed by Orson Welles based on Shakespeare's eponymous play |
| 35% | HOOK | 4 | 1991 film in which Dustin Hoffman plays a pirate captain |
| 35% | LOISLANE | 8 | Reporter played by Amy Adams in "Justice League" (2 wds.) |
| 35% | ZOE | 3 | "House of Cards" reporter played by Kate Mara |
| 35% | THEGRADUATE | 11 | 1967 Dustin Hoffman film |
| 35% | TOOTSIE | 7 | 1982 Dustin Hoffman film |
| 35% | EAR | 3 | Play by ___ (handle on the spot) |
| 35% | CHEF | 4 | 2014 film in which Dustin Hoffman plays an uncreative restaurant owner |
| 35% | TOOTSIE | 7 | 1982 film in which Dustin Hoffman plays a cross-dressing actor |