| 100% | BETTYBOOP | 9 | Cartoon flapper first appearing in 1930 |
| 59% | BOOP | 4 | Betty ___ (curvaceous toon who first appeared in 1930) |
| 56% | YOSEMITESAM | 11 | He first appeared in the cartoon "Hare Trigger" |
| 53% | ABE | 3 | "Simpsons" character who first appeared in the cartoon "Grampa and the Kids" |
| 52% | NANCYDREW | 9 | Fictional girl detective who first appeared in 1930 novel The Secret of the Old Clock by Carolyn Keene |
| 50% | GOOFY | 5 | Walt Disney character originally called Dippy Dawg who first appeared in 1932 animated cartoon Mickey's Revue |
| 48% | TWEETYBIRD | 10 | Cartoon canary who first appeared in 1942's A Tale of Two Kitties |
| 48% | DAFFY | 5 | Cartoon duck who first appeared in the 1937 short "Porky's Duck Hunt" |
| 47% | NANCYDREW | 9 | Fictional young female detective who first appeared in a 1930 book credited to the pen name Carolyn Keene: 2 wds. |
| 45% | AMERICA | 7 | Captain __ first appeared in 1941 |
| 44% | LOLA | 4 | Bunny first appearing in "Space Jam" (1996) |
| 44% | ACTI | 4 | When the witches first appear in "Macbeth" |
| 44% | ACTII | 5 | When Thomas Jefferson first appears in "Hamilton" |
| 43% | CHRIST | 6 | Word that first appears in Matthew 1:1 |
| 43% | POIROT | 6 | Agatha Christie sleuth who first appeared in 1920 |
| 43% | PADME | 5 | Queen who first appears in “The Phantom Menace” |
| 43% | WASP | 4 | Insect that first appeared in the Jurassic era |
| 42% | LOLA | 4 | ___ Bunny (female toon who first appeared in "Space Jam") |
| 42% | YODA | 4 | Alien who first appears in "The Empire Strikes Back" |
| 42% | XENA | 4 | Character who first appeared in "Hercules: The Legendary Journeys" |
| 42% | ICECASTLE | 9 | Temporary structure that first appeared in 1740 in St. Petersburg |
| 42% | WEAKEST | 7 | The __ Link, TV game show first appeared in the UK |
| 42% | GEORGESMILEY | 12 | Fictional spy who first appeared in "Call for the Dead" |
| 41% | NANCYDREW | 9 | Character who first appeared in "The Secret of the Old Clock" |
| 41% | WHICH | 5 | Publication of the Consumers' Association that first appeared in October 1957 |
| 41% | CHAN | 4 | Fictional character who first appeared in "The House Without a Key" |
| 41% | NODDY | 5 | Enid Blyton children's book character who first appeared in 1949 |
| 41% | APU | 3 | Shopkeeper who first appears in the "Simpsons" episode "The Telltale Head" |
| 41% | YODA | 4 | "Star Wars" character who first appears in "The Empire Strikes Back" |
| 41% | MARIOBROS | 9 | Pair of plumbers, one of whom first appeared in "Donkey Kong" |