| 100% | TOMMY | 5 | CBS series featuring Edie Falco as the first woman LAPD chief of police |
| 37% | MANKILLER | 9 | *Wilma ___, first woman elected as Principal Chief of the Cherokee Nation |
| 31% | JANETRENO | 9 | First woman to serve as attorney general of the US: 2 wds. |
| 30% | SAHLE | 5 | ___-Work Zewde, Ethiopian politician who is the first woman to serve as the President of Ethiopia |
| 30% | MIA | 3 | ___ Mottley, Barbadian politician who is the first woman to serve as the Prime Minister of Barbados |
| 30% | DEVI | 4 | Bidya ___ Bhandari, Nepalese politician who is the first woman to serve as the President of Nepal |
| 30% | TOPCOPS | 7 | Early 1990s CBS series about the exploits of real-life police officers |
| 30% | RENO | 4 | Janet, first woman to serve as the Attorney General of the United States |
| 30% | ASTOR | 5 | Nancy —, first woman to sit as an MP in the House of Commons |
| 30% | TYRA | 4 | Banks who was the first African-American woman featured on the cover of "GQ" |
| 29% | ARCHER | 6 | FX animated comedy series featuring H. Jon Benjamin as the voice of a narcissistic spy |
| 29% | CARMENSANDIEGO | 14 | Netflix animated adventure series featuring the voice of 49-Across as the title character (2 wds.) |
| 28% | NEVERHAVEIEVER | 14 | 2020-2023 Netflix series featuring Niecy Nash-Betts as the therapist of teenager Devi Vishwakumar: 4 wds. |
| 28% | MICHELLEOBAMA | 13 | First African-American woman to serve as First Lady of the United States (2 wds.) |
| 27% | PERICLES | 8 | Known as the first citizen of Athens |
| 27% | KAMALAHARRIS | 12 | Former California senator who is the first woman and first person of color to be inaugurated as vice president of the United States (2 wds.) |
| 27% | PARINGMASTER | 12 | Chief of the kitchen police? |
| 27% | FEB | 3 | Month in 2021 when Ngozi Okonjo-Iweala was chosen as the first woman Director-General of WTO (for short) |
| 27% | ELLA | 4 | Fitzgerald known as the First Lady of Song |
| 27% | PELOSI | 6 | First woman Speaker of the House |
| 27% | BIGBANGTHEORY | 13 | The CBS comedy series "Young Sheldon" was created as a spin-off prequel of the hit sitcom "The ___": 3 wds. |
| 27% | ANGIE | 5 | Actress Dickinson of the 1970s TV series "Police Woman" |
| 27% | ELLAFITZGERALD | 14 | Music legend known as the First Lady of Song |
| 27% | EDERLE | 6 | First woman swimmer of the English Channel |
| 27% | ASTOR | 5 | First woman in the House of Commons |
| 26% | EVE | 3 | First woman mentioned in the Book of Genesis |
| 26% | NANCYASTOR | 10 | First woman in the House of Commons (1919) |
| 26% | PELOSI | 6 | First woman to be Speaker of the House |
| 26% | EVITA | 5 | 1997 6-Across starring Madonna as the first lady of Argentina |