| 100% | LENALUTHOR | 10 | CEO of L-Corp played by Katie McGrath in 49-Across (2 wds.) |
| 48% | BERNIEMADOFF | 12 | Disgraced former financier played by 17-Across in "The Wizard of Lies": 2 wds. |
| 46% | STARRCARTER | 11 | Character played by Amandla Stenberg in the movie adaptation of 30-Across: 2 wds. |
| 45% | JONNJONZZ | 9 | Shape-shifting Martian played by David Harewood in 49-Across (2 wds.) |
| 43% | ANTHONYNELSON | 13 | Astronaut played by Larry Hagman in "I Dream of Jeannie": 2 wds. |
| 42% | JACKSPARROW | 11 | Pirate captain played by Johnny Depp in "Pirates of the Caribbean": 2 wds. |
| 42% | JACKSPARROW | 11 | Pirate played by Johnny Depp in the "Pirates of the Caribbean" movies: 2 wds. |
| 42% | HOWARDHUGHES | 12 | Reclusive billionaire played by 18-Across in "Rules Don't Apply: 2 wds. |
| 41% | JOHNNYENGLISH | 13 | Inept British spy played by 49-Across in three films (2 wds.) |
| 41% | SWEENEYTODD | 11 | Barber played by Johnny Depp in the movie subtitled "The Demon Barber of Fleet Street": 2 wds. |
| 41% | JUNEOSBORNE | 11 | Original name of the character played by 30a in the series in 18a: 2 wds. |
| 40% | SUESTORM | 8 | "Invisible Woman" played by Kate Mara in 31-Across: 2 wds. |
| 40% | BENGRIMM | 8 | "The Thing" played by Jamie Bell in 31-Across: 2 wds. |
| 40% | SUGARPLUMFAIRY | 14 | Role played by 16-Across in a 1954 production of "The Nutcracker": 3 wds. |
| 40% | NEWTSCAMANDER | 13 | Character played by 15-Across in "Fantastic Beasts and Where to Find Them": 2 wds. |
| 40% | DOLORESHUERTA | 13 | Civil rights leader, played by Rosario Dawson in the 18-Across biopic, who received a Presidential Medal of Freedom in 2012: 2 wds. |
| 40% | LOISLANE | 8 | Reporter played by Amy Adams in "Man of Steel" (2 wds.) |
| 39% | ELAINEBENES | 11 | Character played by Julia Louis-Dreyfus in "Seinfeld", who is an ex-girlfriend of 32-Across: 2 wds. |
| 39% | VITOCORLEONE | 12 | Mafia don played by both 14-Across and 28-Across in the "Godfather" franchise: 2 wds. |
| 39% | LORETTALYNN | 11 | Country singer played by 44-Across in the 1980 biopic "Coal Miner's Daughter": 2 wds. |
| 39% | CENTURYCYCLE | 12 | Series of 10 plays by 14-Across, including "Fences" and "The Piano Lesson," that chronicle life in Black America over a 100-year span: 2 wds. |
| 39% | AARONBURR | 9 | Historical figure played by Leslie Odom, Jr. in 28-Across: 2 wds. |
| 38% | LITTLEJOE | 9 | "Bonanza" brother played by 49-Across (2 wds.) |
| 38% | CLAIRERANDALL | 13 | Time-traveling nurse played by Caitriona Balfe in the STARZ adaptation of 29-Across (2 wds.) |
| 38% | HARRYCALLAHAN | 13 | Police inspector played by 15-Across in "Sudden Impact": 2 wds. |
| 38% | JAMESOLSEN | 10 | Photographer played by Mehcad Brooks on 49-Across (2 wds.) |
| 38% | GEORGEBAILEY | 12 | Character played by 29-Across in "It's a Wonderful Life" (2 wds.) |
| 38% | BILBOBAGGINS | 12 | Character played by 27-Across in "The Hobbit" films (2 wds.) |
| 38% | LADYMACBETH | 11 | Scheming spouse played by Jeanette Nolan, Alex Kingston, and Marion Cotillard in film versions of a Shakespeare play (2 wds.) |
| 38% | LORDVOLDEMORT | 13 | "Harry Potter" villain played by 49-Across (2 wds.) |