| 100% | POPBOTTLE | 9 | Certain recyclable, in the Midwest |
| 64% | WABASH | 6 | Border river in the Midwest |
| 64% | OHARE | 5 | Busiest airport in the Midwest |
| 64% | OHARE | 5 | Midway alternative in the Midwest |
| 64% | OHARE | 5 | Largest airport in the Midwest |
| 62% | POP | 3 | Soda, in the Midwest |
| 62% | CST | 3 | Winter hrs. in the Midwest |
| 62% | POPB/AUOTTLES | 13 | Soda containers, in the Midwest |
| 60% | COLUMBUSSUMOCLUB | 16 | Heavyweights in the Midwest? |
| 58% | CDT | 3 | Summer setting in the Midwest: Abbr. |
| 58% | BLOOMINGTON | 11 | State university city in the Midwest |
| 58% | FLAT | 4 | Like most land in the Midwest |
| 58% | FARGO | 5 | Crime drama set in the Midwest |
| 58% | WISCONSINCHEESE | 15 | Dairy product made in the Midwest |
| 58% | KCMO | 4 | Jazz mecca in the Midwest, casually |
| 58% | AMES | 4 | City in the Midwest's Story County |
| 58% | LAKES | 5 | "Great" ones are found in the Midwest |
| 58% | OZARK | 5 | Netflix crime drama set in the Midwest |
| 57% | ADDER | 5 | Certain snake in the grass |
| 57% | LANINA | 6 | Cause of a dry spell in the Midwest |
| 57% | URBANA | 6 | It has a twin city in the Midwest |
| 57% | FARGO | 5 | Emmy-winning drama series set in the Midwest |
| 57% | IOWA | 4 | ___ Writers’ Workshop (vaunted graduate program in the Midwest) |
| 56% | CHILI | 5 | Bowlful served with a cinnamon roll in the Midwest |
| 56% | OPE | 3 | "Let me just scoot past you," in the Midwest |
| 56% | TRASHCANON | 10 | Principle like "Always put recyclables in the blue bin"? |
| 55% | SCEPTRE | 7 | Certain object in the British crown jewels |
| 55% | DEERE | 5 | Largest employer in the Midwest's Quad Cities, for short |
| 54% | OHIO | 4 | Easternmost state in the Midwest, per the U.S. Census Bureau |
| 53% | LAKETROUT | 9 | Fish commonly caught in the Upper Midwest |