| 100% | DARWIN | 6 | Charles who developed the theory of evolution |
| 66% | EINSTEIN | 8 | Scientist who developed the theory of relativity |
| 65% | ALBERTEINSTEIN | 14 | Physicist who developed the theory of relativity: 2 wds. |
| 61% | PASCAL | 6 | Blaise —, 17th-century mathematician and philosopher who developed the theory of probability with Pierre de Fermat |
| 56% | STAHL | 5 | Georg Ernst —, German scientist born in 1659 who developed the phlogiston theory of combustion |
| 52% | CHARLESDARWIN | 13 | Biologist who gave the theory of evolution in "On the Origin of Species", that is depicted in the 2009 movie "Creation": 2 wds. |
| 51% | SURVIVAL | 8 | Theory of evolution; __ of the fittest |
| 48% | EINSTEIN | 8 | Scientist who espoused the theory of relativity |
| 47% | EINSTEIN | 8 | The man who discovered the theory of relativity |
| 46% | ASIMOV | 6 | I, Robot sci-fi author who developed the Three Laws of Robotics |
| 46% | HOFFMAN | 7 | German chemist who developed the use of aspirin |
| 45% | BOHR | 4 | Physics Nobelist who developed an early model of the atom |
| 45% | VEBLEN | 6 | Economist who wrote "The Theory of the Leisure Class" |
| 43% | ALSTON | 6 | Charles who created murals for Harlem Hospital and the American Museum of Natural History |
| 43% | DAVIDGRAEBER | 12 | Anthropologist who developed the concept of everyday communism in “Debt: The First 5,000 Years” |
| 42% | DARWIN | 6 | Theory of Evolution |
| 42% | JAMIEFOXX | 9 | Actor who played the role of Ray Charles and Yahya |
| 41% | EULER | 5 | Mathematician who wrote the first theorem of graph theory |
| 41% | PERCY | 5 | Charles ___, character who tragically left the show in season 6 of "Grey's Anatomy" |
| 40% | EDDIEREDMAYNE | 13 | "The Theory of Everything" actor who was nominated for a 2024 Tony for playing the Emcee in "Cabaret": 2 wds. |
| 40% | KEPLER | 6 | Johannes ___, German astronomer, who developed the laws of planetary motion |
| 40% | FERMAT | 6 | French mathematician who pioneered in the theory of probability |
| 39% | JONASSALK | 9 | Virologist who developed the first successful polio vaccine and was awarded the Presidential Medal of Freedom by Jimmy Carter in 1977 (2 wds.) |
| 39% | HUME | 4 | Philosopher who first advanced the "bundle theory" of ontology |
| 39% | LUTHERBURBANK | 13 | Horticulturist who developed the Shasta daisy |
| 39% | IACOCCA | 7 | Auto executive who developed the Mustang |
| 39% | JAMES | 5 | ___ Charles, American influencer who was one of the most searched figures on the Internet in 2019 |
| 39% | FELICITYJONES | 13 | "The Theory of Everything" actress who plays Dr. Sienna Brooks in "Inferno": 2 wds. |
| 38% | JETHRO | 6 | Inventor Tull, who developed the seed drill |
| 38% | LAVOISIER | 9 | French chemist, outlined the theory of combustion |