| 100% | CAPTAINCOLD | 11 | Chilly villain played by Wentworth Miller on "The Flash": 2 wds. |
| 65% | KILLERFROST | 11 | Icy villain played by Danielle Panabaker on "The Flash": 2 wds. |
| 61% | WEATHERWIZARD | 13 | Climate-controlling villain played by Liam McIntyre on "The Flash": 2 wds. |
| 47% | JOEWEST | 7 | Detective played by 30-Across on "The Flash" for nine seasons (2 wds.) |
| 46% | DEREKMORGAN | 11 | Character on the crime drama series "Criminal Minds" played by Shemar Moore: 2 wds. |
| 45% | HALLINDEN | 9 | He played Captain Miller on the 1975-1982 sitcom "Barney Miller": 2 wds. |
| 44% | JOHNSTEED | 9 | Spy played by Patrick Macnee on "The Avengers": 2 wds. |
| 44% | JENNIFERMELFI | 13 | Psychiatrist played by Lorraine Bracco on "The Sopranos": 2 wds. |
| 44% | AVONBARKSDALE | 13 | Drug dealer played by Wood Harris on "The Wire": 2 wds. |
| 43% | KELLYKAPOWSKI | 13 | Bayside cheerleader played by Tiffani Thiessen on "Saved by the Bell": 2 wds. |
| 43% | DEANNATROI | 10 | "Star Trek" character played by Marina Sirtis, who serves as the ship's counselor on USS Enterprise-D: 2 wds. |
| 43% | PIPERCHAPMAN | 12 | Lead character played by Taylor Schilling on "Orange Is the New Black": 2 wds. |
| 43% | RAFESADLER | 10 | Character played by actor Thomas Brodie-Sangster in the British television serial "Wolf Hall" based on Hilary Mantel novels: 2 wds. |
| 42% | LISATURTLE | 10 | Aspiring fashion designer played by Lark Voorhies on "Saved by the Bell": 2 wds. |
| 42% | ALFIESOLOMONS | 13 | "Peaky Blinders" character, played by Tom Hardy, who ran a distillery and was seen on the show from season 2 till 4: 2 wds. |
| 41% | ARCHIEANDREWS | 13 | Comics character played by KJ Apa on The CW's "Riverdale" (2 wds.) |
| 41% | BETTYCOOPER | 11 | Comics character played by Lili Reinhart on The CW's "Riverdale" (2 wds.) |
| 41% | VERONICALODGE | 13 | Comics character played by Camila Mendes on The CW's "Riverdale" (2 wds.) |
| 41% | VERONICALODGE | 13 | Comics character played by Camila Mendes on The CW series "Riverdale" (2 wds.) |
| 41% | PRINCECHARLES | 13 | British royal played by Josh O'Connor on Netflix's "The Crown" in 2020: 2 wds. |
| 41% | OLIVERQUEEN | 11 | Real name of Green Arrow, played by Stephen Amell on the CW's "Arrow": 2 wds. |
| 40% | SHELDONCOOPER | 13 | Geeky character played by Jim Parsons on "The Big Bang Theory": 2 wds. |
| 40% | PRINCESSDIANA | 13 | British royal played by Emma Corrin on "The Crown" in 2020: 2 wds. |
| 40% | QUEENELIZABETH | 14 | British royal played by Olivia Colman on "The Crown" in 2020: 2 wds. |
| 40% | NANCYBOTWIN | 11 | Drug dealer played by Mary-Louise Parker on "Weeds": 2 wds. |
| 40% | NAPOLEONSOLO | 12 | Spy played by Robert Vaughn on "The Man From U.N.C.L.E.": 2 wds. |
| 40% | DRWATSON | 8 | Holmes' assistant, played by 29-Across on 47-Across: 2 wds. |
| 40% | DEREKMORGAN | 11 | Special agent played by 39-Across on 29-Across: 2 wds. |
| 40% | UNCLEJESSE | 10 | Role played by 18-Across on "Full House": 2 wds. |
| 39% | DRIVOROBOTNIK | 13 | Villain played by Jim Carrey in the "Sonic the Hedgehog" films (3 wds.) |