| 100% | ABFAB | 5 | Classic Britcom based on a sketch called “Modern Mother and Daughter,” familiarly |
| 50% | ABFAB | 5 | Britcom based on a "French and Saunders" sketch |
| 38% | MACGRUBER | 9 | 2010 Will Forte/Kristen Wiig film based on a classic "SNL" sketch |
| 38% | CONEHEADS | 9 | 1993 Dan Aykroyd/Jane Curtin film based on a classic "SNL" sketch |
| 37% | WAYNESWORLD | 11 | 1992 Mike Myers/Dana Carvey film based on a classic "SNL" sketch (2 wds.) |
| 33% | RAIN | 4 | Classic play based on a Maugham tale |
| 32% | EYRE | 4 | "Jane ___" (2011 movie based on a classic novel) |
| 31% | THELITTLEPRINCE | 15 | "Royal" film based on a classic children's story, 1974 |
| 31% | THEJUNGLEBOOK | 13 | 2016 movie based on a Rudyard Kipling classic: 3 wds. |
| 31% | WAYNESWORLD | 11 | 1992 comedy based on a long-running "S.N.L." sketch |
| 31% | MOD | 3 | "The ___ Squad" (Claire Danes film based on a classic TV show) |
| 30% | LESMIZ | 6 | 2012 movie musical based on a Victor Hugo novel, familiarly: 2 wds. |
| 29% | READY | 5 | "___ Player One," 2018 sci-fi movie based on a virtual gaming world called OASIS |
| 29% | SHOGUN | 6 | 1980 miniseries based on a James Clavell novel, starring Richard Chamberlain and Toshiro Mifune |
| 29% | CLUE | 4 | 1985 mystery comedy movie based on a board game, starring Michael McKean and Eileen Brennan |
| 29% | ARRIVAL | 7 | 2017 Best Picture Oscar nominee based on a Ted Chiang novella about aliens and linguistics |
| 29% | DOOM | 4 | "___ Patrol," 2019 series based on a DC superhero team featuring Crazy Jane and Elasti-Girl |
| 29% | CLAIRE | 6 | Mother of Haley, Alex, and Luke on Modern Family |
| 29% | HILLBILLYELEGY | 14 | 2020 drama based on a true story with Amy Adams as a troubled mother: 2 wds. |
| 29% | JUDE | 4 | 1996 period drama film based on a Thomas Hardy novel starring Kate Winslet and Christopher Eccleston |
| 29% | NORTHANDSOUTH | 13 | 1985 miniseries based on a John Jakes novel, starring Patrick Swayze and James Read: 3 wds. |
| 29% | THETHORNBIRDS | 13 | 1983 miniseries based on a Colleen McCullough novel, starring Richard Chamberlain and Rachel Ward: 3 wds. |
| 28% | HASH | 4 | Symbol on a computer keyboard also called a number sign and octothorp |
| 28% | FICTION | 7 | A book based on imaginary events and characters |
| 28% | CURIOUSGEORGE | 13 | Will Ferrell film based on a story series by H.A. Rey and Margret Rey (2 wds.) |
| 28% | JUSTMERCY | 9 | Legal drama based on a true story starring Brie Larson, 17-Across, and 32-Across (2 wds.) |
| 28% | ASPIC | 5 | Savoury jelly based on meat or fish stock and set in a mould |
| 28% | ECOWARRIORS | 11 | Based on a common feature of their names, what 17-, 23-, 36- and 51-Across are well-suited to be? |
| 28% | PAPERCARRIERS | 13 | Morning news deliverers ... or based on a hidden word in each, what 20-, 27- and 43-Across are? |
| 28% | BLACKBIRD | 9 | Apple TV+ miniseries based on a true story starring 15-Across, 24-Across, and 30-Across (2 wds.) |