| 100% | MRNOODLE | 8 | Clown played by Bill Irwin on "Sesame Street" (2 wds.) |
| 54% | MRNOODLE | 8 | Mime played by Bill Irwin on "Elmo's World" |
| 47% | UNCLEJESSE | 10 | Role played by 18-Across on "Full House": 2 wds. |
| 46% | ADAMMAYFAIR | 11 | Gynecologist played by Nathan Fillion on "Desperate Housewives": 2 wds. |
| 46% | JOHNSTEED | 9 | Spy played by Patrick Macnee on "The Avengers": 2 wds. |
| 46% | JIMPHELPS | 9 | Spy played by Peter Graves on "Mission: Impossible": 2 wds. |
| 46% | JENNIFERMELFI | 13 | Psychiatrist played by Lorraine Bracco on "The Sopranos": 2 wds. |
| 46% | THEBRIDE | 8 | Sword wielder played by Uma Thurman in "Kill Bill": 2 wds. |
| 46% | NANCYBOTWIN | 11 | Drug dealer played by Mary-Louise Parker on "Weeds": 2 wds. |
| 45% | DRWATSON | 8 | Holmes' assistant, played by 29-Across on 47-Across: 2 wds. |
| 45% | DEREKMORGAN | 11 | Special agent played by 39-Across on 29-Across: 2 wds. |
| 44% | KELLYBUNDY | 10 | Ditzy character played by 15-/50-Across on "Married... with Children": 2 wds. |
| 44% | MICKJAGGER | 10 | Rolling Stones singer played by Nick Eversman in "Get On Up": 2 wds. |
| 44% | LILITHSTERNIN | 13 | Psychiatrist played by Bebe Neuwirth on "Cheers": 2 wds. |
| 44% | COOKIEMONSTER | 13 | Blue Muppet on "Sesame Street": 2 wds. |
| 44% | HOWARDBORDEN | 12 | Bob's neighbor on "The Bob Newhart Show," played by Bill Daily: 2 wds. |
| 44% | ROSSGELLER | 10 | Geeky character played by David Schwimmer on "Friends": 2 wds. |
| 44% | MALREYNOLDS | 11 | Spaceship owner played by Nathan Fillion on "Firefly": 2 wds. |
| 44% | PHOEBEBUFFAY | 12 | Vegetarian masseuse played by Lisa Kudrow on "Friends": 2 wds. |
| 44% | RACHELBERRY | 11 | Vegetarian singer played by Lea Michele on "Glee": 2 wds. |
| 43% | LITTLERICHARD | 13 | "Long Tall Sally" singer played by Brandon Mychal Smith in "Get On Up": 2 wds. |
| 43% | STEVEURKEL | 10 | Geeky character played by Jaleel White on "Family Matters": 2 wds. |
| 43% | AVONBARKSDALE | 13 | Drug dealer played by Wood Harris on "The Wire": 2 wds. |
| 43% | WALTERWHITE | 11 | Drug dealer played by Bryan Cranston on "Breaking Bad": 2 wds. |
| 43% | CAPTAINCOLD | 11 | Chilly villain played by Wentworth Miller on "The Flash": 2 wds. |
| 43% | KILLERFROST | 11 | Icy villain played by Danielle Panabaker on "The Flash": 2 wds. |
| 43% | PRINCECHARLES | 13 | British royal played by Josh O'Connor on Netflix's "The Crown" in 2020: 2 wds. |
| 43% | ALFREDBELLOWS | 13 | Psychiatrist played by Hayden Rorke on "I Dream of Jeannie": 2 wds. |
| 42% | ZACKMORRIS | 10 | Frequent nuisance to Principal Belding played by Mark-Paul Gosselaar on "Saved by the Bell": 2 wds. |
| 41% | JOANCLAYTON | 11 | Character played by Tracee Ellis Ross on 17-Across: 2 wds. |