| 100% | HARLEM | 6 | Colson Whitehead’s “___ Shuffle,” whose narrative centers on a heist at New York City’s historic Hotel Theresa (September, 2021) |
| 30% | HARLEMSHUFFLE | 13 | 2021 Colson Whitehead novel set in New York City (2 wds.) |
| 29% | RYE | 3 | New York city with an amusement park that's a National Historic Landmark |
| 28% | XSQUARE | 7 | Where a New York City ball drops on New Year's Eve |
| 27% | SARATOGASPRINGS | 15 | New York city with a historic race course |
| 27% | WARHOL | 6 | Painter Andy whose "Orange Disaster #5" is on display at New York's Guggenheim Museum |
| 27% | TWA | 3 | Bygone company whose name survives on a hotel at JFK Airport |
| 27% | POLLOCK | 7 | Painter Jackson whose "Autumn Rhythm (Number 30)" is on display at New York's Metropolitan Museum of Art |
| 26% | WALDORF | 7 | New York City hotel that lent its name to a well-known salad |
| 26% | RYE | 3 | New York city on Long Island Sound...and a homophone of 11 Across |
| 26% | JACOBJAVITS | 11 | Politician for whom a New York City convention center is named |
| 26% | ICET | 4 | Rapper who plays a New York City detective on TV: Hyph. |
| 26% | PABLOPICASSO | 12 | Cubist painter whose "Les Demoiselles d'Avignon" is on display at New York's Museum of Modern Art: 2 wds. |
| 26% | MACYS | 5 | Flagship store at New York City's Herald Square |
| 26% | GALA | 4 | Affair at New York City's Met, for one |
| 26% | HARLEMSHUFFLE | 13 | Colson Whitehead novel set in New York City (2 wds.) |
| 26% | GRACIE | 6 | Name on the mansion of New York City's mayor |
| 26% | BROOKLYNDECKER | 14 | "Grace and Frankie" actress whose first name is also a place in New York City (2 wds.) |
| 25% | RUTHDRAPER | 10 | New York City-born monologist whose repertoire included The Italian Lesson and Opening a Bazaar |
| 25% | NELLIEBLY | 9 | Muckraker whose 1887 exposé "Ten Days in a Mad-House" exposed conditions at New York's Women's Lunatic Asylum: 2 wds. |
| 25% | USSMAINE | 8 | Ship with a memorial in New York City's Central Park |
| 25% | SHED | 4 | The ___, arts center in New York City that has an outer shell on wheels |
| 25% | SIENA | 5 | City in Tuscany whose historic center is a UNESCO World Heritage Site |
| 25% | JACOBRIIS | 9 | New York social reformer whose name is on a Manhattan housing project |
| 25% | INSET | 5 | Like Staten Island on a New York City subway map |
| 25% | REGIS | 5 | New York's historic St. ___ Hotel |
| 25% | OPERA | 5 | Offering at New York's Lincoln Center |
| 25% | DRAPER | 6 | Ruth —, New York City-born monologist whose repertoire included The Italian Lesson and Opening a Bazaar |
| 25% | THEDOLLHOUSE | 12 | Novel by 39-Across set in New York City's Barbizon Hotel (2 wds.) |
| 25% | FAME | 4 | 1980 musical film set at New York City's High School of Performing Arts |