| 100% | NADIA | 5 | Comaneci who was the first gymnast to be awarded a perfect ten at the Olympics |
| 76% | NADIA | 5 | ___ Comaneci, the first gymnast to be awarded a perfect score of 10 at the Olympics |
| 51% | COMANECI | 8 | Nadia __, first gymnast to be awarded a perfect 10 |
| 49% | NADIA | 5 | She is a five-time Olympic gold medalist and the first gymnast to score a perfect 10 at the Games |
| 48% | YUTOHORIGOME | 12 | Japanese skateboarder who was the first person to win a gold medal in skateboarding at the Olympics, in men's street skateboarding in Tokyo in 2021 (2 wds.) |
| 47% | COMANECI | 8 | Nadia who was the 1st gymnast to get a perfect 10 |
| 46% | RETTON | 6 | Gymnast Mary Lou who was the first woman to appear on the front of a Wheaties box |
| 46% | SUNILEE | 7 | Gymnast who was the first Hmong American athlete to compete in the Olympics |
| 45% | VVEBDUBOIS | 10 | Historian, essayist and civil rights leader who was the first African American to receive a doctorate at Harvard |
| 44% | JENNA | 5 | Marbles who is the first social-media star to have a wax statue at Madame Tussauds |
| 44% | GWENJORGENSEN | 13 | American distance runner and two-time ITU World Champion who was the first to win a triathlon gold for USA in the Olympics: 2 wds. |
| 43% | ULRIC | 5 | German prelate who was the first person to be canonized, A.D. 993 |
| 42% | HARLANCOBEN | 11 | 17-Across and 30-Across novelist who is the first writer to win an Anthony Award, a Shamus Award, and an Edgar Award (2 wds.) |
| 42% | XAVIERCUGAT | 11 | Entertainer who was the first man to be married at Caesars Palace |
| 42% | CORI | 4 | Gerty Theresa ___, biochemist who was the first woman to be awarded the Nobel Prize in Physiology or Medicine |
| 42% | LORNASIMPSON | 12 | "Projects 23" photographer who was the first African-American woman to have a solo exhibition at the Museum of Modern Art (2 wds.) |
| 41% | TEBOW | 5 | Tim who was the first sophomore to win a Heisman |
| 41% | SALONGA | 7 | Lea who was the first Asian actress to win a Tony |
| 41% | LORRE | 5 | Peter who was the first actor to play a Bond villain |
| 41% | IRA | 3 | Songwriter Gershwin who was the first lyricist to win a Pulitzer |
| 41% | ANG | 3 | Lee who was the first Asian to win a best-director Oscar |
| 41% | RENEE | 5 | Fleming who was the first opera singer to perform the national anthem at the Super Bowl (2014) |
| 40% | LUISE | 5 | Rainer who was the first person to win two Academy Awards for acting |
| 40% | EDITH | 5 | Wharton who was the first woman to win a Pulitzer Prize for fiction |
| 40% | ETHEL | 5 | Waters who was the first Black American to host a national television show |
| 40% | POITIER | 7 | Sidney who was the first African American to win a Best Actor Oscar |
| 40% | JIMTHORPE | 9 | First Native American to win a gold medal at the Olympics |
| 40% | MIRAINAGASU | 11 | First American woman to land a triple axel at the Olympics |
| 40% | COMANECI | 8 | Nadia, the first gymnast to score a perfect 10 |
| 40% | ANGELA | 6 | Bassett who was the first person to be nominated for an Oscar for acting in a Marvel movie |