| 100% | KENANTHOMPSON | 13 | Comedian and "Saturday Night Live" cast member who voices Gus the beaver in 43-Across (2 wds.) |
| 55% | JOHNOLIVER | 10 | Comedian and late-night host who voices Steve the porcupine in 43-Across (2 wds.) |
| 53% | NORMMACDONALD | 13 | "Saturday Night Live" comedian who voiced the dog Lucky in "Dr. Dolittle": 2 wds. |
| 53% | KATEMCKINNON | 12 | "Saturday Night Live" cast member who voices Squeeks the Mouse on PBS Kids' "Nature Cat" (2 wds.) |
| 53% | KENANTHOMPSON | 13 | "Saturday Night Live" comedian who hosted the People's Choice Awards in 2021 and 2022: 2 wds. |
| 52% | CHRISROCK | 9 | "Saturday Night Live" cast member (1990-1993) who voiced the zebra Marty in the "Madagascar" movies: 2 wds. |
| 51% | JENNYSLATE | 10 | Former "Saturday Night Live" comedian who voices the Pomeranian Gidget in "The Secret Life of Pets" films: 2 wds. |
| 50% | GARRETTMORRIS | 13 | Original "Saturday Night Live" cast member who plays the cashier on 15-Across' show: 2 wds. |
| 49% | ADAMSANDLER | 11 | Comedian and former "Saturday Night Live" cast member: 2 wds. |
| 49% | AMYPOEHLER | 10 | "Saturday Night Live" comedian who went on to star in 24-Across and 36-/42-Across: 2 wds. |
| 48% | ANDYSAMBERG | 11 | "Saturday Night Live" cast member who recently ended his seven-year run with the show: 2 wds. |
| 48% | KRISTENWIIG | 11 | "Saturday Night Live" cast member who recently ended her seven-year run with the show: 2 wds. |
| 48% | DANAYKROYD | 10 | Original "Saturday Night Live" cast member who played the Coneheads dad: 2 wds. |
| 48% | EGO | 3 | Former Saturday Night Live cast member who announced her departure from the show in a September Instagram post |
| 48% | KATEMCKINNON | 12 | "Saturday Night Live" cast member who plays talent agent Debra Hammer in 41-Across (2 wds.) |
| 48% | JANECURTIN | 10 | Original "Saturday Night Live" cast member who appeared in "Point-Counterpoint" sketches with 39-Across (2 wds.) |
| 48% | DANAYKROYD | 10 | Original "Saturday Night Live" cast member who appeared in "Point-Counterpoint" sketches with 17-Across (2 wds.) |
| 47% | BILLHADER | 9 | Former "Saturday Night Live" cast member who plays the title role on 4-Across (2 wds.) |
| 45% | KENANTHOMPSON | 13 | Actor who is the longest-running Saturday Night Live cast member, born after the premiere of SNL (42nd anniversary today): 2 wds. |
| 45% | WILLFERRELL | 11 | "Elf" actor and "Saturday Night Live" star who won the Mark Twain Prize for American Humor in 2011: 2 wds. |
| 45% | JASONSUDEIKIS | 13 | "Saturday Night Live" cast member who threatened to end his seven-year run with the show but is back for the 2012-2013 season: 2 wds. |
| 45% | TRACYMORGAN | 11 | Former "Saturday Night Live" cast member who hosted the 2019 ESPY Awards ceremony (2 wds.) |
| 44% | FREDARMISEN | 11 | Former "Saturday Night Live" comedian who cocreated and frequently appears on 34-Across: 2 wds. |
| 43% | BILLYCRYSTAL | 12 | "SNL" cast member (1984-1985) who voiced Mike Wazowski in the "Monsters, Inc." movies: 2 wds. |
| 43% | JOHNBELUSHI | 11 | Original "Saturday Night Live" cast member who played a samurai: 2 wds. |
| 43% | JANECURTIN | 10 | Original "Saturday Night Live" cast member who played Mrs. Loopner: 2 wds. |
| 43% | GILDARADNER | 11 | Original "Saturday Night Live" cast member who played Emily Litella: 2 wds. |
| 42% | KENANTHOMPSON | 13 | "Saturday Night Live" comedian who hosted the Nickelodeon Kids' Choice Awards in 2021: 2 wds. |
| 42% | ANDYSAMBERG | 11 | Former "Saturday Night Live" cast member who plays 34-Across on 15-Across/41-Across (2 wds.) |
| 41% | RUSSELLBRAND | 12 | Comedian and voice actor in "Despicable Me" who has his own podcast, ''Under the Skin'' which is a mix of intellectual interrogations: 2 wds. |