| 100% | BOBBYMOYNIHAN | 13 | Comedy actor who voices Panda on "We Bare Bears" (2 wds.) |
| 78% | ERICEDELSTEIN | 13 | Comedy actor who voices Grizzly on the Cartoon Network's "We Bare Bears" (2 wds.) |
| 78% | DEMETRIMARTIN | 13 | Comedy actor who voices Ice Bear on "We Bare Bears" (2 wds.) |
| 54% | HARRYSHEARER | 12 | Actor who voices Principal Seymour Skinner on "The Simpsons": 2 wds. |
| 53% | SETHGREEN | 9 | Actor who voices Chris Griffin on "Family Guy": 2 wds. |
| 52% | CHRISPARNELL | 12 | Former "SNL" actor who voices Cyril Figgis on "Archer": 2 wds. |
| 52% | RONFUNCHES | 10 | "Undateable" actor who voices King Shark on "Harley Quinn": 2 wds. |
| 52% | TONYHALE | 8 | "Veep" actor who voices Doctor Psycho on "Harley Quinn": 2 wds. |
| 51% | TREYPARKER | 10 | "BASEketball" actor who voices teacher Herbert Garrison on "South Park": 2 wds. |
| 51% | PATTONOSWALT | 12 | "Ratatouille" actor who voices Matthew the Raven on "The Sandman": 2 wds. |
| 51% | BENFELDMAN | 10 | "Superstore" actor who voices Avi Schwooper on "Long Story Short": 2 wds. |
| 50% | ADAMSANDLER | 11 | "Happy Gilmore" actor who voiced a vampire in the "Hotel Transylvania" comedies: 2 wds. |
| 50% | SETHROGEN | 9 | "Steve Jobs" actor who voices Master Mantis in the "Kung Fu Panda" franchise: 2 wds. |
| 50% | JACKBLACK | 9 | "Shallow Hal" actor who voices Master Po in the "Kung Fu Panda" franchise: 2 wds. |
| 50% | JERRYOCONNELL | 13 | "Sliders" actor who voices first officer Jack Ransom on "Star Trek: Lower Decks": 2 wds. |
| 50% | JACKQUAID | 9 | "The Boys" actor who voices ensign Brad Boimler on "Star Trek: Lower Decks": 2 wds. |
| 49% | EDHELMS | 7 | Actor who portrays Andy Bernard on the US television show "The Office": 2 wds. |
| 49% | JOHNKRASINSKI | 13 | Actor who portrays Jim Halpert on the US television show "The Office": 2 wds. |
| 49% | JOHNDIMAGGIO | 12 | Actor who voices the robot Bender on "Futurama" (2 wds.) |
| 49% | ISAACHAYES | 10 | Actor/singer who voiced Chef on "South Park": 2 wds. |
| 48% | GARYCOLE | 8 | "Veep" actor who voices Principal Shepherd on 45-Across (2 wds.) |
| 48% | PAULREISER | 10 | "Mad About You" actor who voices Elliot Cooper on the Netflix animated series "Long Story Short": 2 wds. |
| 47% | WILWHEATON | 10 | "Star Trek: The Next Generation" actor who voices amnesiac chef Earl Harlan, a character on 15-/51-Across: 2 wds. |
| 47% | JOHNCENA | 8 | "Blockers" actor who voices a polar bear in 33-Across (2 wds.) |
| 47% | CORYMONTEITH | 12 | "Glee" actor who we lost on 7/13/13: 2 wds. |
| 46% | WILLARNETT | 10 | "Arrested Development" actor who voices the title character on 32-Across (2 wds.) |
| 46% | ADAMWEST | 8 | "Batman" actor who voices himself on 45-Across (2 wds.) |
| 46% | BRADLEYCOOPER | 13 | Actor who had a song from "A Star Is Born" chart on the Billboard Hot 100 in 2018: 2 wds. |
| 46% | TERRYCREWS | 10 | "Brooklyn Nine-Nine" actor who skydived over Iceland on "Running Wild With Bear Grylls" in 2021: 2 wds. |
| 46% | DANNYTREJO | 10 | "Machete" actor who zip-lined down a mountain on "Running Wild With Bear Grylls" in 2021: 2 wds. |