| 100% | BROADCITY | 9 | Comedy Central sitcom that starred Ilana Glazer and Abbi Jacobson: 2 wds. |
| 52% | BROADCITY | 9 | American sitcom based on Ilana Glazer and Abbi Jacobson's real life friendship which will air its ending with the final season this year (2019): 2 wds. |
| 39% | BROAD | 5 | "___ City," TV show starring Abbi Jacobson and Ilana Glazer that is set in New York City |
| 37% | THEINTERNSHIP | 13 | Comedy set at Google that stars 39-Across and Owen Wilson: 2 wds. |
| 36% | POLICEACADEMY | 13 | 1984 comedy starring Steve Guttenberg and Kim Cattrall that led to six sequels, a sitcom, and an animated series (2 wds.) |
| 36% | SOUTHPARK | 9 | Emmy-winning animated Comedy Central sitcom created by Trey Parker and Matt Stone: 2 wds. |
| 36% | APBIO | 5 | Sitcom that starred Glenn Howerton as a high school science teacher: 2 wds. |
| 35% | SUDDENLYSUSAN | 13 | Sitcom starring 15-Across and 32-Across that premiered in 1996 (2 wds.) |
| 34% | BROADCITY | 9 | Sitcom about Abbi and Ilana in the Big Apple: 2 wds. |
| 34% | THEJEFFERSONS | 13 | Sitcom starring Sherman Hemsley and 15-Across that debuted January 18, 1975 (2 wds.) |
| 33% | BROAD | 5 | Ilana Glazer/Abbi Jacobson sitcom "___ City" |
| 33% | MODERNFAMILY | 12 | Sitcom that has won the Emmy for Oustanding Comedy Series five years running: 2 wds. |
| 32% | CURBYOUR | 8 | With 38-Across, 2000-2024 HBO sitcom that centers around a comedy writer and his friends: 2 wds. |
| 32% | LALAW | 5 | Former NBC drama that starred Harry Hamlin and Susan Dey: 2 wds. |
| 32% | COUGARTOWN | 10 | 2009-2015 ABC/TBS sitcom that starred "Friends" alum Courteney Cox as a single mom on the dating scene: 2 wds. |
| 31% | DATENIGHT | 9 | 2010 comedy starring Steve Carell and Tina Fey: 2 wds. |
| 31% | KNOCKEDUP | 9 | 2007 comedy starring Paul Rudd and Seth Rogen: 2 wds. |
| 31% | BADTEACHER | 10 | 2011 comedy starring Justin Timberlake and Cameron Diaz: 2 wds. |
| 31% | RIDEALONG | 9 | 2014 comedy starring Ice Cube and Kevin Hart: 2 wds. |
| 31% | EASYA | 5 | 2010 comedy starring Emma Stone and Penn Badgley: 2 wds. |
| 31% | FREAKDANCE | 10 | 2011 comedy starring Amy Poehler and Matt Besser: 2 wds. |
| 31% | OHGOD | 5 | 1977 comedy starring John Denver and George Burns: 2 wds. |
| 31% | BROADCITY | 9 | Recently ended sitcom on Comedy Central: 2 wds. |
| 30% | FRIENDSWITH | 11 | "___ Benefits," 2011 romantic comedy film that starred Justin Timberlake and Mila Kunis in the lead roles: 2 wds. |
| 30% | ROSEANNEBARR | 12 | 1990s sitcom star who was the subject of a Comedy Central Roast in 2012: 2 wds. |
| 30% | SOUTHPARK | 9 | Comedy Central animated series that wrapped its 25th season in 2022: 2 wds. |
| 30% | BLUESBROTHERS | 13 | 1980 comedy starring John Belushi and Dan Aykroyd, with "The": 2 wds. |
| 30% | MASH | 4 | Sitcom that starred Alan Alda and Loretta Swit |
| 30% | TAXI | 4 | Sitcom that starred Judd Hirsch and Danny DeVito |
| 30% | SANFORDANDSON | 13 | Sitcom starring Redd Foxx and Demond Wilson that premiered on January 14, 1972 (3 wds.) |