| 100% | REUSE | 5 | Companion of reduce and recycle |
| 52% | VISHNU | 6 | Companion of Brahma and Shiva |
| 52% | TALL | 4 | Companion of dark and handsome |
| 52% | TOM | 3 | Companion of Dick and Harry |
| 52% | YON | 3 | Companion of hither and thither |
| 52% | SNAP | 4 | Companion of Crackle and Pop |
| 52% | ATHOS | 5 | Companion of Aramis and Porthos |
| 52% | BUTCH | 5 | Companion of Rex and Rover |
| 52% | ATHOS | 5 | Companion of Porthos and Aramis |
| 52% | ETTA | 4 | Companion of Butch and Sundance |
| 52% | PAST | 4 | Companion of present and future |
| 52% | ETHOS | 5 | Companion of logos and pathos |
| 51% | CYAN | 4 | Companion of magenta, yellow and black |
| 50% | NINA | 4 | Companion of the Pinta and Santa Maria |
| 50% | PINTA | 5 | Companion of the Niña and Santa Maria |
| 50% | PAST | 4 | Companion of the present and the future |
| 49% | PINTA | 5 | Companion of the Niña and the Santa Maria |
| 48% | INIGO | 5 | Companion of Westley and Fezzik in "The Princess Bride" |
| 48% | EUROPA | 6 | Companion of Io, Ganymede and Callisto among Jupiter's moons |
| 47% | RABBI | 5 | Companion of a priest and a minister in many a joke |
| 46% | PISTOL | 6 | Companion of Falstaff in Henry V and other plays by William Shakespeare |
| 46% | ETTAPLACE | 9 | *Real-life companion of Butch Cassidy and the Sundance Kid |
| 45% | PERKY | 5 | Puppet pig, companion of Pinky, created by Jan and Vlasta Dalibor |
| 45% | PINKY | 5 | Puppet pig, companion of Perky, created by Jan and Vlasta Dalibor |
| 43% | FRED | 4 | "Mystery Machine" companion of Daphne and Velma |
| 43% | BAYMAX | 6 | Inflatable healthcare companion of Hiro who is his voice of guidance and safety |
| 43% | SKINK | 5 | Lizard of tropical Asia and Africa with reduced limbs |
| 40% | FRIENDSTOTHEEND | 15 | Lifelong companions, and a feature of 17-, 27-, 37- and 45-Across |
| 38% | OREAD | 5 | Companion of Artemis |
| 38% | URIEL | 5 | Companion of Gabriel |