| 100% | THC | 3 | Compound that's in most of your joints (abbr.) |
| 48% | MBA | 3 | Degree that started materialising in the early 20's, and is one of the most sought after courses nowadays : Abbr. |
| 46% | TNT | 3 | Explosive compound that's also the name of a TV channel: Abbr. |
| 45% | FYI | 3 | Abbr. that's at the start of many forwarded emails |
| 44% | MDS | 3 | Most of the main characters in "Private Practice": Abbr. |
| 43% | IRE | 3 | Source of much U.S. immigration in the 1840s: Abbr. |
| 43% | IDLY | 4 | Just sitting there without having much of your brain in gear |
| 43% | EURO | 4 | Currency that's accepted in most of one continent |
| 42% | UNTO | 4 | Preposition that’s one of the most used words in the Book of Mormon |
| 42% | NORWAY | 6 | Country that's won the most medals in the history of the Winter Olympics |
| 42% | ALA | 3 | Southern state that's first alphabetically in a list of the 50 states: Abbr. |
| 42% | NOSTRIL | 7 | Part of your body that smells the most? |
| 42% | CROP | 4 | Something of interest that's in your own field |
| 42% | MOIST | 5 | Adjective that's been called "one of the most hated words in the English language" |
| 42% | ERA | 3 | Time period that's often the savior of many crossword constructors (as in this instance) |
| 41% | WWI | 3 | Conflict that began in the wake of Franz Ferdinand’s assassination: Abbr. |
| 41% | LOBE | 4 | The part of your ear that is most commonly pierced |
| 41% | MYSPACE | 7 | News Corporation-owned Web site that's one of the 10 most visited sites in the world |
| 41% | UCLA | 4 | West Coast school that received the most applications of any US school in 2017: Abbr. |
| 40% | DEADSKIN | 8 | Most dust particles in your house are made of __ |
| 40% | PHD | 3 | Degree that many strive for in grad school: Abbr. |
| 40% | PTA | 3 | Group that encourages participation of parents in school: Abbr. |
| 40% | TNT | 3 | Compound that's similar to dynamite: Abbr. |
| 40% | KUDZU | 5 | Plant that has become invasive in much of the Eastern U.S. |
| 39% | PERPETUALMOTRIN | 15 | In what state are many of your customers? |
| 39% | IRS | 3 | Agency that receives many returns in April: Abbr. |
| 39% | IRS | 3 | Agency that many people curse in April: Abbr. |
| 39% | CEL | 3 | One of many that Bugs Bunny appeared in |
| 39% | ESTER | 5 | Compound that’s an anagram of “trees” |
| 39% | ASS | 3 | Animal in many of 38-Down's fables |