| 100% | TNT | 3 | Compound that explodes: Abbr. |
| 70% | TNT | 3 | Stuff that explodes: Abbr. |
| 67% | TNT | 3 | Compound that goes "boom": Abbr. |
| 66% | TNT | 3 | Compound that blows things up: Abbr. |
| 64% | TNT | 3 | Compound that's similar to dynamite: Abbr. |
| 63% | TNT | 3 | Compound that could make a big bang: Abbr. |
| 57% | TNT | 3 | Explosive compound that's also the name of a TV channel: Abbr. |
| 52% | THC | 3 | Compound that's in most of your joints (abbr.) |
| 48% | TNT | 3 | Compound that goes BOOM |
| 47% | BOMB | 4 | Weapon that explodes |
| 46% | ENOL | 4 | Compound that's subject to tautomerism |
| 46% | ETHANOL | 7 | Compound that makes a drink alcoholic |
| 46% | AMINE | 5 | Compound that's derived from ammonia |
| 46% | ALKALI | 6 | Compound that turns litmus paper blue |
| 46% | ANILINES | 8 | Compounds that smell of rotting fish |
| 45% | TNT | 3 | Exploding compound |
| 45% | MGMT | 4 | Those in charge: Abbr. |
| 45% | ESTER | 5 | Compound that gives many fruits their scent |
| 45% | ESTER | 5 | Compound that’s an anagram of “trees” |
| 45% | AMIDES | 6 | Compounds that can be carbox- or phospor- |
| 44% | PREBIOTIC | 9 | Compound that promotes healthy bacteria in the gut |
| 44% | STYRENE | 7 | Compound that may leach from some takeout containers |
| 43% | ESTERS | 6 | Compounds that contribute to beer's fruity flavor |
| 43% | HISTAMINE | 9 | A cell compound that attacks allergens |
| 43% | BAKELITE | 8 | Chemical compound that makes synthetic plastic |
| 43% | MENTHOL | 7 | Peppermint compound that clears blocked sinuses |
| 43% | CHOLINE | 7 | Naturally found compound that synthesizes lipids |
| 43% | FERRITE | 7 | Ceramic iron compound that's nonconductive |
| 43% | LYE | 3 | Washing compound that sounds like "lie" |
| 43% | HISTAMINE | 9 | A cell compound that attacks allergies |