| 100% | UPARROW | 7 | Computer key that might make a video game character jump |
| 45% | SIM | 3 | Video game character that might WooHoo |
| 43% | ESC | 3 | Computer key that one might press in a panic |
| 39% | SIM | 3 | Computer game character that might be "Hot-Headed" or "Unflirty" |
| 38% | FLAVORTEXT | 10 | Words that add depth to a video game character |
| 38% | DONKEYKONG | 10 | Video game with a gorilla that first featured the main character of 43-Across (2 wds.) |
| 38% | TAB | 3 | Computer key used to indent that you may press to pay your "bill at a restaurant"? |
| 38% | SPACE | 5 | Character that's entered via the longest key on a computer keyboard |
| 37% | LEVELUP | 7 | Improve a video game character's abilities |
| 37% | POPQUIZ | 7 | Surprise that might make a pupil shrink? |
| 37% | FLEA | 4 | Insect that might make a dog itch |
| 37% | SEND | 4 | Button that might make a "Whoosh!" sound |
| 37% | STAY | 4 | Word that might make a boxer freeze |
| 37% | LEMONDROP | 9 | Cocktail that may make a drinker pucker |
| 37% | IRON | 4 | Laundry implement that might make a 43-Down |
| 37% | PLAYDOH | 7 | Clay for kids that might make a mess? |
| 37% | TMI | 3 | Letters that might make a long story short? |
| 37% | TREAT | 5 | Word that may make a dog sit up |
| 37% | ESC | 3 | Key that may close a window |
| 36% | ERASERS | 7 | Things that might make a cloud when clapped together |
| 36% | OTTER | 5 | Animal that might make a waterslide to play on |
| 36% | ESC | 3 | Key that might close a dialog box |
| 36% | MARIO | 5 | Video game character with a large mustache |
| 36% | LUIGI | 5 | Video game character in a green hat |
| 36% | SIM | 3 | Video game character speaking a gibberish language |
| 36% | SIM | 3 | Video game character in a virtual city |
| 36% | BACKSPACE | 9 | Computer key that deletes the last character typed |
| 36% | ISLE | 4 | Key that might be part of a chain |
| 36% | SONIC | 5 | Video game character in a hit 2020 film |
| 36% | MINECRAFT | 9 | A video game world entirely made of blocks |