| 100% | BELIEFS | 7 | Convictions a person has about the meaning of life |
| 46% | PARISIAN | 8 | A person who lives in the capital of France |
| 43% | LIFESPAN | 8 | The length of time for which a person lives |
| 42% | WORKLOAD | 8 | The amount of labor a person has to do |
| 42% | UNREAL | 6 | Drama TV series about the life of a dating show producer starring Shiri Appleby |
| 42% | MISTAKEN | 8 | In a case of __ identity you have the wrong person |
| 42% | PHILOSOPHICALLY | 15 | Relating to the meaning of life |
| 41% | BFF | 3 | Person who might have the other half of a heart necklace, in brief |
| 41% | DRINK | 5 | "Eat ___ Man Woman," 1994 Ang Lee movie about the family life of a semi-retired chef |
| 41% | NOMAD | 5 | Person who lives a life of little pleasures, wandering about from place to place |
| 41% | ALEXA | 5 | "___, what is the meaning of life?" (modern query) |
| 40% | BED | 3 | Where most people spend about a third of their life |
| 39% | STUFFING | 8 | The meaning of farce in a French restaurant |
| 39% | DEFINE | 6 | Describe the meaning of a word |
| 39% | DEFINING | 8 | Explaining the meaning of a word |
| 39% | INTERPRET | 9 | Explain the meaning of a dream |
| 39% | OURMISSINGHARTS | 15 | Celeste Ng novel about the absence of male deer in people's lives? |
| 39% | SIRI | 4 | iPhone assistant who says that "42" is the meaning of life |
| 39% | JAWSOFLIFE | 10 | Firefighter's term for lengthy gabfests about the meaning of existence? |
| 39% | DEFINE | 6 | Explain the meaning of, as a word |
| 39% | EBAY | 4 | Where the meaning of life was sold in 2000 for $3.26 |
| 39% | THE | 3 | "All in ___ Family," CBS sitcom about the life of a working-class father and his family that ran from 1971 - 1979 |
| 38% | CHILDHOOD | 9 | Youth, the youngest years of a person's life |
| 38% | MIND | 4 | “The Life of the ___,” Christine Smallwood novel about lost opportunities to become a mother and professor (March, 2021) |
| 38% | DEFINE | 6 | Provide the meaning of, as in a dictionary |
| 38% | IAMCAIT | 7 | E! reality series about the post-transition life of a “Keeping Up with the Kardashians” cast member |
| 38% | NOT | 3 | Word that completely changes the meaning of a sentence |
| 38% | RUGRATS | 7 | Animated series about Tommy Pickles and his friends which had a Halloween episode titled "Curse of the Werewuff" |
| 38% | MILES | 5 | A marathon has about 26 of these |
| 38% | SEEDS | 5 | A strawberry has about 200 of these |