| 100% | DUBLINMURDERS | 13 | Crime series set in Ireland based on Tana French novels (2 wds.) |
| 89% | DUBLINMURDERS | 13 | BBC/Starz crime series set in Ireland based on novels by Tana French (2 wds.) |
| 51% | ALTEREDCARBON | 13 | Netflix series, based on a cyberpunk novel, set more than 300 years in the future: 2 wds. |
| 42% | HIGHFIDELITY | 12 | Film based on a Nick Hornby novel set in a record shop starring John Cusack and Joan Cusack (2 wds.) |
| 42% | SWEETMAGNOLIAS | 14 | Netflix series based on Sherryl Woods novels about three friends in South Carolina (2 wds.) |
| 41% | TELLMEASTORY | 12 | CBS All Access series set in a dark, modern-day world based on classic fairy tales: 4 wds. |
| 41% | QUEENSUGAR | 10 | OWN series based on a Natalie Baszile novel about a family farm in Louisiana (2 wds.) |
| 41% | JACKTAYLOR | 10 | Mystery drama series set in Ireland starring Iain Glen as a private investigator (2 wds.) |
| 40% | THEFALL | 7 | Serial killer crime series set in Northern Ireland |
| 39% | THESEARCHER | 11 | 2020 novel by Tana French about a retired detective who begins investigating an old mystery in rural Ireland (2 wds.) |
| 38% | THEGOLDBERGS | 12 | ABC comedy series set in the 1980s: 2 wds. |
| 38% | STRANGERTHINGS | 14 | Netflix horror series set in the 1980s: 2 wds. |
| 38% | THEAMERICANS | 12 | FX spy series set in the 1980s: 2 wds. |
| 38% | ADVENTURETIME | 13 | Animated Cartoon Network series set in the Land of Ooo: 2 wds. |
| 37% | FAMILYGUY | 9 | Animated Fox series set in Quahog, Rhode Island: 2 wds. |
| 37% | YOGIBEAR | 8 | "The ___ Show," animated series set in Jellystone Park: 2 wds. |
| 37% | SOUTHPARK | 9 | Long-running animated series set in the Rockies: 2 wds. |
| 37% | DERRYGIRLS | 10 | British TV series set at Our Lady Immaculate secondary school in Northern Ireland (2 wds.) |
| 36% | SOUTHPARK | 9 | Animated Comedy Central series set in a small town in Colorado: 2 wds. |
| 36% | RYANSDAUGHTER | 13 | 1970 romantic epic directed by David Lean and set in Ireland: 2 wds. |
| 36% | AGENT | 5 | "___ Carter," TV series set in the 1940s based on Marvel Comics character Peggy Carter |
| 36% | TRUEBLOOD | 9 | HBO show based on a series of Charlaine Harris books: 2 wds. |
| 36% | LESMIZ | 6 | 2012 movie musical based on a Victor Hugo novel, familiarly: 2 wds. |
| 36% | THESENTINEL | 11 | A 2006 crime thriller based on Gerald Petievich's novel, starring 18a and Michael Douglas: 2 wds. |
| 35% | ORANGEIS | 8 | With 33- and 52-Across, television series set in a women's prison: 2 wds. |
| 35% | CATCH | 5 | "Halt and ___ Fire," TV series set in the 1980s based on the revolution of personal computers |
| 35% | AMERICANGODS | 12 | Television series based on 45a's novel which is about Shadow Moon, a former convict and Mr. Wednesday, a con artist: 2 wds. |
| 35% | MAISEL | 6 | "The Marvelous Mrs. ___," TV series set in the 1960s based on the comedic journey of a housewife |
| 34% | THEGOLDFINCH | 12 | 2019 film based on a 2013 best-selling novel by Donna Tartt: 2 wds. |
| 34% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |