| 100% | INDEPENDENCEAVE | 15 | D.C. thoroughfare with the Smithsonian's National Air and Space Museum |
| 66% | MOONROCKS | 9 | Some are displayed in the Smithsonian's National Air and Space Museum |
| 46% | IMAX | 4 | National Air and Space Museum film format |
| 36% | ELMO | 4 | Red Muppet in the Smithsonian’s National Museum of American History |
| 32% | HOPE | 4 | ___ Diamond, display at the Smithsonian National History Museum |
| 32% | RENO | 4 | Nevada city with the National Automobile Museum |
| 32% | SELMA | 5 | City that’s home to the National Voting Rights Museum and Institute |
| 31% | NMENTAGENCY | 11 | The National Aeronautics and Space Administration, for one |
| 31% | AIR | 3 | National ___ and Space Museum (Washington, DC attraction) |
| 31% | ALPHABETTIES | 12 | Neckwear with the letters A, B, C, D, etc.? |
| 31% | CLARITY | 7 | One of the four C's of diamonds (along with cut, color, and carat) |
| 31% | AMSTERDAM | 9 | City with the Anne Frank House and Van Gogh Museum |
| 30% | TESLA | 5 | Automaker with the Model S and Model X |
| 30% | TBS | 3 | Cable channel with the animated shows "Final Space" and "American Dad!" |
| 30% | WARDROBE | 8 | The Lion, the Witch and the __, by C. S. Lewis |
| 30% | FORESTER | 8 | C S —, author of novels The Commodore and Lord Hornblower |
| 29% | TESLA | 5 | Car company with the models S and X |
| 29% | AISLE | 5 | With 7-Across, what C and D indicate on boarding passes |
| 29% | RNA | 3 | Molecule with the bases G, U, A, and C |
| 29% | TEXAS | 5 | Location of the National Cowgirl Museum and Hall of Fame |
| 29% | GOODBYE | 7 | With 32-Across and 54-Across, title of the final episode of "M*A*S*H," which aired February 28, 1983 |
| 28% | AERO | 4 | Prefix with "space" to collectively mean the atmosphere and outer space |
| 28% | OCANADA | 7 | National anthem with the lyric “The True North strong and free!” |
| 28% | OCANADA | 7 | National anthem with the line "The True North strong and free" |
| 28% | MCA | 3 | Member of the Beastie Boys with Mike D and Ad-Rock |
| 28% | PHYSICS | 7 | Branch of science concerned with the study of the properties of space, time, matter and energy |
| 28% | UNITEDKINGDOMOF | 15 | With 37- and 56-Across, where "God Save the Queen" is the national anthem |
| 28% | OUTOFTHE | 8 | & 22A 1938 C S Lewis novel; first part of the Space Trilogy |
| 28% | PHYSICS | 7 | That branch of science concerned with the study of the properties of space, time, matter and energy |
| 27% | OCASIO | 6 | With 13-Across, the "O" and "C" of the political world's A.O.C. |