| 100% | JOHNNYENGLISH | 13 | A comically incompetent spy for "MI7," created as a parody of 50a, and portrayed by Rowan Atkinson in the films by the same name: 2 wds. |
| 98% | AGENTORANGE | 11 | Highly poisonous herbicide used as a spray for crop destruction by the US during the Vietnam War |
| 93% | SOYLENT | 7 | Drinkable meal created by a software engineer in 2013 |
| 90% | UNCONDITIONAL | 13 | "____ Love," a song by Tupac Shakur released posthumously in 1999, as a part of his "Greatest Hits" album. |
| 90% | JERRY | 5 | Fictional sitcom within a sitcom created by the titular character of "Seinfeld" with his friend, George Costanza |
| 89% | UREA | 4 | Substance that showed, in 1828, that something previously produced only as a by-product of life, could be created in the lab |
| 89% | PELOPS | 6 | Son of Tantalus in Greek mythology killed by his father and served to the gods as a meal |
| 88% | PGTHIRTEEN | 10 | Somewhat family-friendly ... or a title for this puzzle, as suggested by the completed grid? |
| 87% | AGENT | 5 | & 6D Highly poisonous herbicide used as a spray for defoliation and crop destruction by the US during the Vietnam War |
| 85% | PETER | 5 | ___ Griffin, "Family Guy" dad who misuses his powers as a mall Santa, only to be confronted by the actual Santa for the troubles he caused |
| 83% | LABCOAT | 7 | Wear for a chemist, or for a canine, as shown by the starts of 18-, 24-, 51- and 61-Across |
| 83% | DIOR | 4 | Designer whose name, as noted by Jean Cocteau, sounds like a portmanteau of the French words for “God” and “gold” |
| 82% | BUYSOUT | 7 | Takes over the assets of, as a partner |
| 81% | WAITOUT | 7 | Do nothing during the course of, as a storm |
| 81% | CARRY | 5 | Do most of the work for, as a team |
| 81% | CORFE | 5 | & 16D Village on the Isle of Purbeck, Dorset, housing a fortification famous for its defence by Lady Bankes against a parliamentary army during the English Civil War |
| 81% | DELIVERY | 8 | Contactless ___, term popularized during the pandemic to mean a new way of receiving packages |
| 81% | WORKCATION | 10 | Term popularized during the pandemic to mean a combination of holidays and remote jobs |
| 81% | PITT | 4 | Card-___, team created by a temporary merger and now known as the Arizona Cardinals |
| 81% | SELFIES | 7 | Photos described as a "ubiquitous symbol of millennial navel-gazing" by The New Yorker |
| 80% | WHATITSWORTH | 12 | "For ___," the third single by 17a, meant to be released as part of his solo album: 3 wds. |
| 79% | GAP | 3 | Space created by the loss of a baby tooth, e.g. |
| 79% | LIES | 4 | "Love ___," hit song by Khalid and Normani which is a part of the soundtrack for "Love, Simon" |
| 78% | JOHNLARROQUETTE | 15 | Winner of four consecutive Emmys for his sitcom role as a prosecutor |
| 78% | RENT | 4 | "Seasons of Love" musical adapted as a 2005 film by Chris Columbus |
| 78% | PIMIENTO | 8 | Variety of red sweet pepper used as a stuffing for green olives |
| 78% | BLOOM | 5 | Orlando ___, "Pirates of the Caribbean" actor who skydived in a wingsuit for his show "To the Edge" |
| 78% | TOGETHER | 8 | "We Belong ___," a song by Mariah Carey that was listed as Billboard's "Song of the Decade" |
| 78% | TENCIENTS | 9 | Total value of the symbols created by the special crossings in this puzzle |