| 100% | REEL | 4 | Dance that was first referred to in the 1590 witchcraft trial of Doctor Fian in "Edenbrough", Scotland |
| 34% | CUBA | 4 | Havana's island country that is often referred to as the "sugar bowl of the world" |
| 33% | LITTLEBIGHORN | 13 | Iconic site in Montana, that preserves the site of the battle that was fought here, commonly referred to as "Custer's Last Stand": 2 wds. |
| 32% | STTERESA | 8 | First woman to be named Doctor of the Church, briefly |
| 32% | SHALOMMEIRTOWER | 15 | Tel Aviv skyscraper that was the first to be built in the Mideast |
| 32% | PALM | 4 | Co. that was the first to successfully market a PDA worldwide in 1997 |
| 32% | STTERESA | 8 | First woman to be made doctor of the Roman Catholic Church |
| 32% | INCISORS | 8 | Teeth that are typically the first to grow in |
| 32% | CERES | 5 | Body in our solar system that was considered a planet in the first half of the 19th century |
| 32% | TMZ | 3 | Hollywood website that was the first to report Michael Jackson's death in 2009 |
| 32% | CDC | 3 | Org. that was the successor to the Office of Malaria Control in War Areas |
| 32% | MARATSA{FIN} | 12 | First Russian to be inducted in the International Tennis Hall of Fame |
| 32% | ODESSA | 6 | City that was home to the first car in Russia |
| 32% | MYSPACE | 7 | Social networking giant of the '00s that was the first to reach a global audience |
| 31% | CAP | 3 | Surgical ___, headwear worn in the operating room to maintain sterilization that could be a part of your "Doctor" Halloween costume |
| 31% | USN | 3 | JFK was the first president to have served in this branch of the US Armed Forces |
| 31% | QUAIDORSAY | 10 | Street in Paris whose name is used figuratively to refer to the French Ministry of Foreign Affairs |
| 31% | ACHY | 4 | First word in the title of the Billy Ray Cyrus song that popularized line dancing |
| 31% | SAMBAS | 6 | Dances from Brazil that were added to the UNESCO Intangible Cultural Heritage List in 2005 |
| 31% | NEIL | 4 | First name in NASA's prestigious list of astronauts who have been to the moon |
| 31% | SARAHPALIN | 10 | In 2006, she became the first woman to be elected governor of Alaska: 2 wds. |
| 31% | ERNANI | 6 | Verdi work that was the first opera to be recorded in its entirety |
| 31% | OBERLIN | 7 | Ohio college that was the first in the U.S. to admit women |
| 31% | THISISLANDEARTH | 15 | 1955 sci-fi film that was one of the first to use Technicolor |
| 31% | METS | 4 | M.L.B. team that was the first to trade a player for himself (Harry Chiti in 1962) |
| 31% | TOOMUCHHEAVEN | 13 | Song that was the first of three #1 singles by 42-Across in 1979 (3 wds.) |
| 31% | SOH | 3 | The note that was "a needle pulling thread" according to Maria in "The Sound of Music" |
| 31% | SUSANAMARTINEZ | 14 | In 2010, she became the first woman to be elected governor of New Mexico: 2 wds. |
| 31% | NIKKIHALEY | 10 | In 2010, she became the first woman to be elected governor of South Carolina: 2 wds. |
| 31% | CAN | 3 | "Breakfast ___ Wait," song by Prince that refers to the first meal of the day |