| 100% | MENACE | 6 | Dennis the ___ and Gnasher (comic strip partners) |
| 57% | PEARLSBEFORESWINE | 17 | Comic strip with the characters Rat and Pig |
| 56% | FOXTROT | 7 | Comic strip with the kids Peter, Paige and Jason |
| 55% | BLONDIE | 7 | Comic strip featuring the Bumsteads and their children, Alexander and Cookie |
| 52% | BABYBLUES | 9 | Comic strip featuring the MacPhersons and their children, Zoe, Hammie, and Wren (2 wds.) |
| 52% | HIANDLOIS | 9 | Comic strip featuring the Flagstons and their children, Chip, Dot, Ditto, and Trixie (3 wds.) |
| 50% | POGO | 4 | Comic strip that popularized the anti-pollution message “We have met the enemy and he is us” |
| 48% | MOE | 3 | Bully in the comic strip "Calvin and Hobbes" |
| 48% | OPUS | 4 | Penguin in the comic strips "Bloom County" and "Outland" |
| 48% | MENACE | 6 | Dennis is this in the comic strip |
| 48% | TIGER | 5 | Hobbes, in the comic strip "Calvin and Hobbes" |
| 47% | CATANA | 6 | ___ Comics, webcomic based on the everyday life of the titular character and her partner John |
| 46% | ARLO | 4 | Comic strip "___ and Janis" |
| 45% | MENACE | 6 | Comic strip kid Dennis is one |
| 45% | PEANUTS | 7 | Comic strip with Lucy and Linus |
| 45% | FORBETTERORFORWORSE | 19 | Comic strip about the Patterson family |
| 44% | PEANUTS | 7 | Comic strip with Snoopy and Charlie Brown |
| 44% | PEANUTS | 7 | Comic strip featuring Charlie Brown and Snoopy |
| 44% | PEANUTS | 7 | Comic strip about Snoopy and Charlie Brown |
| 44% | ARLO | 4 | American comic strip "___ and Janis" |
| 44% | MENACE | 6 | "Dennis the ___" (comic strip) |
| 43% | GETFUZZY | 8 | Comic strip featuring Satchel Pooch and Bucky Katt |
| 43% | PEANUTS | 7 | Comic strip with Charlie Brown and 44-Across |
| 43% | POGO | 4 | Comic strip featuring Albert Alligator and Porky Pine |
| 43% | HOBBES | 6 | American comic strip series, Calvin and __ |
| 43% | CALVIN | 6 | Hobbes' partner in crime in the comic strip |
| 42% | JAMESGARFIELD | 13 | Popular comic strip at the White House? |
| 42% | FAM | 3 | Partner and the kids, briefly |
| 42% | DILBERT | 7 | Comic strip about a technically minded engineer and his workplace |