| 100% | ASKS | 4 | Dickinson's "The Heart __ Pleasure First" |
| 81% | ASKS | 4 | ''The heart __ pleasure first'': Dickinson |
| 57% | PLEASURE | 8 | Nyman's piano piece, The Heart Asks __ First |
| 53% | SOVIET | 6 | The first S in USSR |
| 53% | ACLUB | 5 | "Not with ___ the heart is broken": Emily Dickinson |
| 51% | HATTER | 6 | First witness called during the trial of the Knave of Hearts, in "Alice's Adventures in Wonderland" |
| 51% | SELF | 4 | The first "S" in S.A.S.E. |
| 51% | SOV | 3 | The first "S" in S.S.R.: Abbr. |
| 51% | MLK | 3 | First president of the S.C.L.C. |
| 51% | BARNARD | 7 | Christiaan __ performed the first heart transplant |
| 49% | AORTA | 5 | The heart's major artery |
| 49% | AORTA | 5 | The heart's main artery |
| 48% | SOVIET | 6 | What the first S in USSR stood for |
| 48% | SOVIET | 6 | What the first S stood for in USSR |
| 48% | MELBOURNE | 9 | 1956 Olympics site, the first in the S hemisphere |
| 46% | HOPE | 4 | Dickinson's singer ''without the words'' |
| 46% | ATRIA | 5 | Two of the heart's chambers |
| 46% | RIB | 3 | Part of the heart's cage? |
| 45% | VENTRICLE | 9 | The heart's two lower chambers: right and left __ |
| 45% | HOME | 4 | Where the heart is, it's said |
| 45% | TORUS | 5 | Shape of the heart's electromagnetic field |
| 45% | AORTICVALVE | 11 | Outlet from the heart's left ventricle |
| 45% | SOVIET | 6 | The first "S" in USSR |
| 45% | SOVIET | 6 | The first "S" in "USSR" |
| 45% | WASTELAND | 9 | The —, modernist poem in five sections by T S Eliot first published in 1922 |
| 45% | IVANA | 5 | The Donald's first |
| 45% | CIRCULATE | 9 | The heart's job is to __ blood throughout the body |
| 44% | HOME | 4 | Where the heart is, so it’s said |
| 44% | JILL | 4 | The First Lady's first name |
| 44% | SSE | 3 | The direction to Hussein's heart |