| 100% | CASE | 4 | Difference between oo and OO |
| 66% | DEUCE | 5 | Difference between 19 and 21 |
| 66% | SPREAD | 6 | Difference between winners and losers? |
| 66% | TENSE | 5 | Difference between is and was |
| 66% | PEE | 3 | Difference between icky and picky? |
| 66% | TENSE | 5 | Difference between lead and led |
| 65% | SECONDS | 7 | Difference between winning and losing, maybe |
| 64% | SPREAD | 6 | Difference between bid and stock asking prices |
| 64% | BALANCE | 7 | Difference between debits and credits in accounts |
| 64% | TENSE | 5 | Difference between “put” and “put” |
| 63% | CHANGE | 6 | Difference between cost and money given to cashier |
| 63% | TANLINE | 7 | Difference between dark and light, in a way |
| 63% | BALANCE | 7 | Trade __, difference between imports and exports |
| 63% | ANO | 3 | The difference between Jan and Joan? |
| 63% | ANI | 3 | The difference between Mara and Maria? |
| 62% | BLURREDLINE | 11 | The difference between ethical and unethical, sometimes |
| 62% | ONE | 3 | ___ hundred, the difference between 1922 and 2022 |
| 62% | GAP | 3 | Trade ___ (value difference between imports and exports) |
| 60% | SPREAD | 6 | Difference between prices bid and asked |
| 59% | PRACTICE | 8 | "The difference between ordinary and extraordinary," per Vladimir Horowitz |
| 59% | EDGE | 4 | It can be the difference between winning and losing |
| 59% | HORN | 4 | Difference between a unicorn and a horse |
| 59% | INCOMEGAP | 9 | Difference between the rich and the poor |
| 58% | HALFSTEP | 8 | Difference between a B and a C, perhaps |
| 57% | DESSERTEDUCATOR | 15 | Someone who teaches people the difference between flan and creme brulee? |
| 57% | ONE | 3 | Difference between a baker's dozen and a dozen |
| 57% | TENSE | 5 | What might be the difference between "read" and "read" |
| 56% | ANE | 3 | The difference between regular mail and e-mail? |
| 56% | HEMLINE | 7 | The difference between a mini and a midi |
| 54% | ANS | 3 | The difference between what he said and what she said |