| 100% | SPREAD | 6 | Difference between prices bid and asked |
| 81% | SPREAD | 6 | Difference between bid and stock asking prices |
| 44% | DEUCE | 5 | Difference between 19 and 21 |
| 44% | SPREAD | 6 | Difference between winners and losers? |
| 44% | CASE | 4 | Difference between oo and OO |
| 44% | TENSE | 5 | Difference between is and was |
| 44% | PEE | 3 | Difference between icky and picky? |
| 44% | TENSE | 5 | Difference between lead and led |
| 44% | TENSE | 5 | Difference between “put” and “put” |
| 43% | SECONDS | 7 | Difference between winning and losing, maybe |
| 42% | BALANCE | 7 | Difference between debits and credits in accounts |
| 42% | CHANGE | 6 | Difference between cost and money given to cashier |
| 42% | TANLINE | 7 | Difference between dark and light, in a way |
| 42% | BALANCE | 7 | Trade __, difference between imports and exports |
| 42% | ANO | 3 | The difference between Jan and Joan? |
| 42% | ANI | 3 | The difference between Mara and Maria? |
| 41% | ONE | 3 | Difference between a baker's dozen and a dozen |
| 41% | HORN | 4 | Difference between a unicorn and a horse |
| 41% | INCOMEGAP | 9 | Difference between the rich and the poor |
| 41% | BLURREDLINE | 11 | The difference between ethical and unethical, sometimes |
| 41% | ONE | 3 | ___ hundred, the difference between 1922 and 2022 |
| 41% | GAP | 3 | Trade ___ (value difference between imports and exports) |
| 40% | HALFSTEP | 8 | Difference between a B and a C, perhaps |
| 39% | PRACTICE | 8 | "The difference between ordinary and extraordinary," per Vladimir Horowitz |
| 39% | EDGE | 4 | It can be the difference between winning and losing |
| 39% | ANS | 3 | The difference between what he said and what she said |
| 39% | TENSE | 5 | The difference between who I was and who I am? |
| 38% | DESSERTEDUCATOR | 15 | Someone who teaches people the difference between flan and creme brulee? |
| 37% | ATTIRE | 6 | Difference between a well-dressed bicyclist and a poorly dressed unicyclist, in a joke |