| 100% | ANOTHER | 7 | Different from the one first considered, one more |
| 49% | VARIANT | 7 | Spelling that's different from the commonly used one |
| 47% | GIANT | 5 | Colossal (this one's a little different from the other eight words) |
| 47% | POPE | 4 | Francis is the first one from the Americas |
| 47% | ESPY | 4 | Award whose name is one letter different from the channel that originated it |
| 46% | FRONTIER | 8 | Many consider space the last great one |
| 46% | DOOM | 4 | First-person shooter game released in 1993 by id Software which is considered to be one of the most influential video games of all time |
| 46% | ERAGON | 6 | Fantasy title character whose name is one letter different from the creature he rides |
| 46% | RUPAULSDRAGRACE | 15 | *Reality show since 2009 (Note: This one's a bit different from the others) |
| 45% | LULL | 4 | Break in the action (only one letter different from 19-Down) |
| 43% | ELLA | 4 | ___ Fitzgerald, singer dubbed the "First Lady of Song" with 14 Grammy Awards and is considered one of the most influential figures in jazz |
| 43% | KHAN | 4 | One of the most popular actors from Bollywood, also known as "King ___" |
| 43% | ISOTOPE | 7 | One of two or more atoms with the same atomic number that contain different numbers of neutrons |
| 42% | ODD | 3 | Different from the norm |
| 42% | ODD | 3 | Different from the normal |
| 42% | JAPAN | 5 | Origin of "The Tale of Genji," considered by many to be the world's first novel |
| 41% | REM | 3 | Georgia band considered to be one of the first alternative rock groups |
| 41% | KANYE | 5 | First name of the rapper who once said “I am the number one most impactful artist of our generation" |
| 41% | SCUBA | 5 | Egypt's "Blue Hole" known for 'the arch' is considered one of the most dangerous ___ diving spots in the world |
| 41% | ALEXANDER | 9 | ___ the Great, a Greek commander who is widely considered to be one of history's most successful military commanders |
| 40% | JOHN | 4 | ___ Coltrane, saxophonist and "A Love Supreme" musician who is considered one of the most influential figures in jazz |
| 40% | LEAP | 4 | "That's one small step for man, one giant ___ for mankind." NASA's first words from the moon |
| 40% | TIDIEST | 7 | The one that is the most neat |
| 40% | GLUE | 4 | Neanderthals made the first one from birch bark tar approximately 200,000 years ago |
| 40% | LOUIS | 5 | ___ Armstrong, trumpeter and "What a Wonderful World" musician who is considered one of the most influential figures in jazz |
| 40% | SPEARS | 6 | The surname of Baby One More Time singer |
| 40% | BIL | 3 | Cartoonist Keane who dropped the second “L” from his first name “just to be different” |
| 39% | AORTA | 5 | One from the heart |
| 39% | ASH | 3 | One from the hearth? |
| 39% | AMERICAN | 8 | One from the States? |