| 100% | SARS | 4 | Disease in an early-two-thousands outbreak, familiarly |
| 49% | SARS | 4 | Outbreak in early-two-thousands news |
| 45% | REBA | 4 | McEntire who had an eponymous sitcom in the early two-thousands |
| 42% | OLDE | 4 | Aged, in an earlier age |
| 42% | ETERNE | 6 | Ageless, in an earlier age |
| 41% | BASICTRAINING | 13 | Instruction in an early computer language? |
| 41% | CANARY | 6 | Bird in an early warning system |
| 41% | ECTODERM | 8 | External layer in an early embryo |
| 40% | PRIMITIVE | 9 | Describes something in an early evolutionary form |
| 40% | NEOPETS | 7 | Virtual animals in an early 2000s fad |
| 40% | SIM | 3 | Character in an early city-building video game |
| 40% | WIMPLE | 6 | Garb in an early ''Sound of Music'' lyric |
| 39% | ECOLI | 5 | Bacteria in an outbreak |
| 39% | PSA | 3 | Smokey Bear was in an early one, for short |
| 38% | TECHBUBBLE | 10 | It burst in the early two-thousands and sent dot-com stocks tumbling |
| 38% | BASS | 4 | Big Mouth Billy ___ (singing fish prop in an early-2000s fad) |
| 37% | HUGUENOT | 8 | Many an early French settler in America |
| 37% | PRIMITIVE | 9 | Relating to an early stage in development |
| 37% | IRA | 3 | An early withdrawal from this incurs a penalty, in brief |
| 36% | UPTHREAD | 8 | Earlier in an Internet-forum discussion |
| 36% | TORSO | 5 | Line drawn after an early wrong guess in hangman |
| 36% | LEO | 3 | He has an early cameo in most 007 films |
| 36% | PAR | 3 | Two more than an eagle, in golf |
| 35% | POINSETTIA | 10 | Plant named for an early U.S. diplomat in Mexico |
| 35% | NAPTIME | 7 | An hour or two in the afternoon, maybe |
| 35% | SPARE | 5 | Ten in two on an alley |
| 35% | SICE | 4 | Best throw you could get on a die in an early English game of Hazard |
| 35% | LONEPAIR | 8 | In an atom's outer shell, two electrons not bonded to another atom |
| 35% | LICE | 4 | Parasites that can be in an outbreak at an elementary school |
| 35% | YWCA | 4 | Grp. that opened an early employment bureau in New York City |