| 100% | HERB | 4 | Doctor Melnick played by Ryan Stiles on "Two and a Half Men" |
| 59% | ALAN | 4 | Brother played by Jon Cryer on "Two and a Half Men" |
| 57% | ALAN | 4 | ___ Harper, character played by Jon Cryer on "Two and a Half Men" |
| 50% | ALAN | 4 | Charlie's brother in "Two and a Half Men," played by Jon Cryer |
| 49% | ALAN | 4 | Jon played him on "Two and a Half Men" |
| 49% | ASHTONKUTCHER | 13 | "Two and a Half Men" actor who played Michael Kelso on "That '70s Show": 2 wds. |
| 46% | JON | 3 | Cryer who plays Alan Harper on "Two and a Half Men" |
| 45% | ALAN | 4 | Chiropractor on "Two and a Half Men" |
| 45% | JAKE | 4 | Teenaged son on "Two and a Half Men" |
| 44% | ALAN | 4 | Jake's father on "Two and a Half Men" |
| 44% | ALAN | 4 | Charlie's brother on "Two and a Half Men" |
| 44% | JAKE | 4 | Alan's son on "Two and a Half Men" |
| 43% | LORRE | 5 | Two and a Half Men co-creator, Chuck __ |
| 41% | ASHTONKUTCHER | 13 | Actor who replaced Charlie Sheen on "Two and a Half Men": 2 wds. |
| 41% | EVELYN | 6 | ___ Harper, Charlie's mother on "Two and a Half Men" |
| 41% | HARPER | 6 | Surname of the brothers in Two and a Half Men |
| 41% | ALAN | 4 | One of the men on "Two and a Half Men" |
| 39% | CHARLIESHEEN | 12 | "Two and a Half Men" actor who was a roastee on Comedy Central Roast with Seth MacFarlane as the roast master: 2 wds. |
| 39% | ALAN | 4 | "Two and a Half Men" role |
| 39% | CBS | 3 | "Two and a Half Men" network |
| 38% | MEN | 3 | There are two and a half of them on a CBS sitcom |
| 38% | AMBER | 5 | "Two and a Half Men" actress Tamblyn |
| 38% | ASHTON | 6 | "Two and a Half Men" star Kutcher |
| 38% | CRYER | 5 | "Two and a Half Men" star Jon |
| 38% | CRYER | 5 | "Two and a Half Men" co-star |
| 38% | MALIBU | 6 | "Two and a Half Men" beach setting |
| 38% | SHEEN | 5 | "Two and a Half Men" star Charlie |
| 38% | LORRE | 5 | "Two and a Half Men" creator Chuck ___ |
| 38% | CRYER | 5 | "Two and a Half Men" co-star Jon |
| 38% | SHEEN | 5 | Charlie of "Two and a Half Men" |