| 100% | PARENTHOOD | 10 | Dramedy about the Braverman family starring Peter Krause, Lauren Graham, and 42-Across |
| 37% | BLESSTHISMESS | 13 | Sitcom about the Levine-Young family starring Ed Begley Jr., Lake Bell, and 42-Across (3 wds.) |
| 31% | MODERNFAMILY | 12 | A TV show about the Pritchett and Dunphy family, in which Sofia Vergara stars: 2 wds. |
| 29% | CROODS | 6 | "The ___," 2013 animated comedy movie about a family of cavemen, starring the voices of Nicolas Cage and Ryan Reynolds |
| 27% | OSBOURNES | 9 | The __, show starring Ozzy, Sharon and family |
| 27% | SIXFEETUNDER | 12 | 2001-05 US television comedy-drama series starring Peter Krause and Michael C Hall |
| 26% | LARRY | 5 | Sly and the Family Stone bassist Graham |
| 26% | JERK | 4 | The —, 1979 comedy film starring Steve Martin and Bernadette Peters |
| 26% | INSECURE | 8 | HBO dramedy about two female best friends, created by and starring Issa Rae |
| 26% | DOWNTONABBEY | 12 | PBS "Masterpiece" series about the Earl of Grantham and his family: 2 wds. |
| 26% | SAVINGMRBANKS | 13 | 2013 film about the making of 33-Across starring Emma Thompson as 18-Across and Tom Hanks as Walt Disney (3 wds.) |
| 26% | MASK | 4 | The —, 1994 action-comedy film starring Jim Carrey and Peter Riegert |
| 26% | CANDIDATE | 9 | The —, 1972 comedy-drama film starring Robert Redford and Peter Boyle |
| 26% | WIZ | 3 | The —, 1978 family film that starred Diana Ross and Michael Jackson |
| 25% | THEOTHERTWO | 11 | HBO Max comedy starring 16-Across and 28-Across about a family dealing with the sudden fame of a younger sibling (3 wds.) |
| 25% | BRIGHTLIGHTS | 12 | HBO documentary about the mother-daughter relationship of 32- and 42-Across: 2 wds. |
| 25% | PILLOWBOOK | 10 | The —, 1996 Peter Greenaway film drama starring Vivian Wu and Ewan McGregor |
| 25% | GURU | 4 | The —, 2002 comedy starring Heather Graham, Marisa Tomei and Jimi Mistry |
| 25% | PAINHUSTLERS | 12 | Netflix crime drama about the pharmaceutical industry starring Emily Blunt and 31-Across (2 wds.) |
| 25% | OSBOURNE | 8 | Family name of Ozzy and Jack, the stars of A&E's "World Detour" |
| 24% | BOBO | 4 | The —, 1967 romcom starring Peter Sellers and Britt Ekland |
| 24% | ADAM | 4 | Kristina and ___ Braverman, fictional couple from the family comedy drama TV series "Parenthood" |
| 24% | COMEDANCING | 11 | Kinks hit about the local palais, and what can be found in the answers to the starred clues? |
| 24% | GRIFFINS | 8 | The ___, "Family Guy" family helmed by Peter and Lois, featuring their children Meg, Chris, and Stewie |
| 24% | JOSIE | 5 | "___ and the Pussycats," 2001 film about an all-girl rock group starring Rachael Leigh Cook |
| 24% | GOING | 5 | With 39- and 42-Across, activity of the spirits in this puzzle |
| 23% | JANETHEVIRGIN | 13 | The CW dramedy starring 49-Across (3 wds.) |
| 23% | WHERES | 6 | "___ the Money?" 2017 comedy starring King Bach and Kat Graham, with a question in the title |
| 23% | BUSEYS | 6 | "The Buddy Holly Story" star and family |
| 23% | STAINS | 6 | "Ladies and Gentlemen, The Fabulous ___," 1982 film about an all-girl band starring Diane Lane |