| 100% | EDDY | 4 | Ed and Edd's buddy, in the cartoons |
| 51% | JINKS | 5 | Pixie and Dixie's nemesis, in the cartoons |
| 47% | ABE | 3 | "Simpsons" character who first appeared in the cartoon "Grampa and the Kids" |
| 46% | ODIE | 4 | Dog in the former TV cartoon "Garfield and Friends" |
| 44% | TOM | 3 | Jerry's catcher, in the cartoons |
| 44% | TOM | 3 | Jerry's frenemy, in the cartoons |
| 44% | REN | 3 | Stimpy's friend, in the cartoons |
| 44% | TOM | 3 | Jerry's nemesis, in the cartoons |
| 44% | REN | 3 | Stimpy's pal, in the cartoons |
| 44% | TOM | 3 | Jerry's frenemy in the cartoons |
| 44% | YVESSAINT | 9 | The Y and the S in YSL, French fashion designer |
| 44% | STU | 3 | Phil, Alan, and Doug's buddy in "The Hangover" |
| 43% | SYNDROME | 8 | It's the S in AIDS, IBS and PMS |
| 43% | WILMA | 5 | Betty's buddy, in cartoons |
| 42% | AMIGO | 5 | Buddy in the barrio |
| 42% | BRO | 3 | Buddy in the 'hood |
| 42% | ANGER | 5 | Ed ___ who wrote "Let's Pave the Stupid Rainforests & Give School Teachers Stun Guns: And Other Ways to Save America" in 1996 |
| 42% | HOLOGRAMS | 9 | Buddy Holly and Tupac when performing in the 2010s |
| 41% | JEFF | 4 | Mutt's buddy, in the comics |
| 41% | TOM | 3 | Jerry's gray-furred nemesis, in the cartoons |
| 41% | PUMBAA | 6 | Timon's warthog buddy in The Lion King |
| 41% | FALKOR | 6 | Bastian's dragon buddy in The NeverEnding Story |
| 41% | EUGENE | 6 | Wednesday's bee buddy in the TV series |
| 41% | PAUL | 4 | ___ Newman, actor known for his role in the Western buddy film "Butch Cassidy and the Sundance Kid" |
| 41% | FARO | 4 | Port and resort in the Algarve, S Portugal |
| 41% | GEOLOGIST | 9 | Expert in the Earth's rocks and minerals |
| 40% | OYL | 3 | Olive in the cartoons |
| 40% | OYL | 3 | Olive ___, spinach-eating sailor's gal in the cartoons |
| 40% | ATESTS | 6 | Big news in the 40's and 50's |
| 40% | IDOL | 4 | Elvis Presley, in the 50's and 60's |