| 100% | JENNER | 6 | Edward, English scientist who invented vaccination |
| 48% | HOOKE | 5 | English scientist who coined the biological term "cell" |
| 46% | NEWTON | 6 | Sir Isaac ___, scientist who invented the color wheel |
| 45% | EDWARDJENNER | 12 | English scientist who is known for the smallpox vaccine: 2 wds. |
| 45% | MARIATELKES | 11 | Scientist who invented and designed the first solar-powered home (2 wds.) |
| 42% | JENNER | 6 | Edward -, English pioneer of vaccination; ‘the father of immunology’ |
| 40% | TEACH | 5 | Edward —, English pirate also known as Blackbeard who died in 1718 |
| 40% | JETHRO | 6 | & 21D English agriculturist who invented the seed drill |
| 39% | HOOKE | 5 | Robert —, English scientist born in 1635 who built the first Gregorian telescope |
| 38% | CRAIG | 5 | Edward Gordon —, English theatrical designer and actor who died in 1966 |
| 37% | TULL | 4 | Jethro —, English agriculturist who invented the seed drill |
| 37% | DAVY | 4 | Humphry —, English chemist who invented a miners' safety lamp |
| 36% | CARL{SAGA}N | 11 | Scientist who said, “If you wish to make an apple pie from scratch, you must first invent the universe” |
| 34% | ALANTURING | 10 | English computer scientist who pioneered the breaking of ciphers generated by the 98-Across |
| 33% | FLEMING | 7 | Scientist who discovered Penicillin |
| 33% | BIOLOGIST | 9 | Scientist who studies living things |
| 33% | NOBEL | 5 | Scientist who discovered dynamite, Alfred __ |
| 32% | CHEMIST | 7 | Scientist who researches elements and compounds |
| 32% | ISAACNEWTON | 11 | Scientist who experienced a great fall? |
| 32% | CHEMIST | 7 | Scientist who works with test tubes |
| 32% | PHYSICIST | 9 | Scientist who studies a natural science |
| 32% | CHEMIST | 7 | Scientist who works with reactive substances |
| 32% | CHEMIST | 7 | Scientist who creates potions with elements |
| 32% | MARIECURIE | 10 | Scientist who coined the term “radioactivity” |
| 32% | NAPIER | 6 | John who invented logarithms |
| 32% | ISAAC | 5 | ___ Pitman, who invented shorthand |
| 32% | JMBARRIE | 8 | Author who invented Neverland |
| 32% | WRIGHT | 6 | Brothers who invented planes |
| 32% | KWOLEK | 6 | Stephanie __, who invented Kevlar |
| 32% | NAISMITH | 8 | James who invented basketball |