| 100% | BROOKE | 6 | Edward ___, first popularly elected African-American U.S. senator (Massachusetts, 1967-79) |
| 37% | AMYKLOBU | 8 | *Minnesota's first elected female U.S. senator |
| 37% | FAYETTEVILLE | 12 | Where Senator Hiram Rhodes Revels, first African American to serve in the U.S. Congress, was born |
| 35% | RITA | 4 | Dove, who became the first African American U.S. Poet Laureate |
| 34% | EDWARDBROOKE | 12 | African-American U.S. Senator who introduced legislation to create a holiday honoring Martin Luther King Jr. (2 wds.) |
| 34% | BRAGG | 5 | Alvin ___, first African American to be elected Manhattan's district attorney |
| 33% | LORETTA | 7 | ___ Lynch, first African American woman to serve as U.S. attorney general |
| 33% | OBAMA | 5 | Barack ___, first African-American president of the U.S. |
| 33% | RITADOVE | 8 | *First African-American U.S. poet laureate |
| 33% | ATLARGE | 7 | How U.S. senators are elected |
| 33% | XXXXXXXX | 8 | First African-American woman to hold the post of U.S. poet laureate |
| 31% | LEE | 3 | Rebecca ___ Crumpler, first African-American female physician in the U.S. |
| 31% | CLAIREMCCASKILL | 15 | Missouri's first elected female senator |
| 30% | VERN | 4 | U.S. Representative Buchanan of Florida, first elected in November 2006 |
| 30% | MAGGIEHASSAN | 12 | New Hampshire governor elected to her first term as a US senator in 2016: 2 wds. |
| 30% | KAMALAHARRIS | 12 | California attorney general elected to her first term as a US senator in 2016: 2 wds. |
| 28% | TAMMYDUCKWORTH | 14 | Illinois congresswoman and Iraq War veteran elected to her first term as a US senator in 2016: 2 wds. |
| 28% | HARRIS | 6 | Stayce, first African American to reach three star general rank in the US Air Force (2016) |
| 28% | HIRAM | 5 | U. S. Grant's given first name |
| 27% | ERIC | 4 | Holder who was the first African-American US Attorney General |
| 27% | ROBINSON | 8 | First African American MLB player, Jackie __ |
| 27% | SHIRLEYCHISHOLM | 15 | First Black woman elected to the U.S. Congress |
| 27% | EDMONIALEWIS | 12 | African-American and Native American sculptor who is honored on a 2022 U.S. postage stamp (2 wds.) |
| 26% | KWANZAA | 7 | US African American festival, ends on January 1 |
| 26% | BERNIE | 6 | U.S. Senator ___ Sanders |
| 26% | CORY | 4 | U.S. Senator Booker |
| 26% | BESSIECOLEMAN | 13 | First woman of African-American and Native American descent to earn an international pilot's license (2 wds.) |
| 25% | RUBIO | 5 | U.S. senator from Florida |
| 25% | ZAILAAVANTGARDE | 15 | First African American to win the Scripps National Spelling Bee |
| 25% | CHISHOLM | 8 | Shirley, first Black woman elected to US Congress |