| 100% | DOUG | 4 | Emhoff, who's the first second gentleman |
| 76% | DOUG | 4 | Emhoff who will be the first Second Gentleman of the United States |
| 61% | DOUG | 4 | First second gentleman Emhoff |
| 56% | DOUG | 4 | Second Gentleman of the United States Emhoff |
| 45% | DOUG | 4 | Second gentleman Emhoff |
| 44% | NOONE | 5 | Who's on first, at the top of the inning |
| 44% | JILLBIDEN | 9 | Current US First Lady who was also the Second Lady from 2009 to 2017: 2 wds. |
| 44% | SOVIET | 6 | The first S in USSR |
| 43% | DOUG | 4 | Current Second Gentleman ___ Emhoff |
| 43% | DOUG | 4 | Former Second Gentleman Emhoff |
| 43% | MARX | 4 | Who said history repeats itself "the first time as tragedy, the second time as farce" |
| 43% | REGIS | 5 | Philbin who was the first host of "America's Got Talent" |
| 42% | NONE | 4 | First pronoun in the last paragraph of Lincoln's Second Inaugural Address |
| 42% | STU | 3 | Rasmussen who was the first openly transgender mayor in the U.S. |
| 42% | ESTELLE | 7 | Princess who's second in line of succession to the Swedish throne |
| 42% | EDIE | 4 | First name of the actress who plays Tommy on CBS's "Tommy" |
| 42% | MARSAIMARTIN | 12 | Producer who was the first cover star of Essence's Girls United |
| 42% | IKE | 3 | First name of the musician who was Tina Turner's ex-husband |
| 42% | RITA | 4 | Dove, who became the first African American U.S. Poet Laureate |
| 42% | ABIGAILADAMS | 12 | US First Lady from 1797 to 1801 who was also the Second Lady from 1789 to 1797: 2 wds. |
| 42% | BETTYFORD | 9 | US First Lady from 1974 to 1977 who was also the Second Lady from 1973 to 1974: 2 wds. |
| 42% | RODCAREW | 8 | Minnesota Twins first and second baseman who was inducted into the Baseball Hall of Fame in 1991: 2 wds. |
| 42% | WALLIS | 6 | Simpson who was Time's first Woman of the Year |
| 42% | AARON | 5 | First ''Who's Who in the Bible'' entry |
| 42% | SELF | 4 | The first "S" in S.A.S.E. |
| 42% | SOV | 3 | The first "S" in S.S.R.: Abbr. |
| 41% | BIL | 3 | Cartoonist Keane who dropped the second “L” from his first name “just to be different” |
| 41% | RIC | 3 | Flair who was the first wrestler to complete the WCW's Triple Crown |
| 41% | JASON | 5 | Kidd who's second all-time in assists and steals in the NBA |