| 100% | EDWARDJENNER | 12 | English scientist who is known for the smallpox vaccine: 2 wds. |
| 56% | PAULMCCARTNEY | 13 | English songwriter who was the bass guitarist for the Beatles and is known for his song "Band on the run": 2 wds. |
| 53% | SHERILYNFENN | 12 | Actress who is known for playing Audrey Horne in the cult TV series "Twin Peaks": 2 wds. |
| 52% | KYLEMACLACHLAN | 14 | Actor who is known for playing Special Agent Dale Cooper in the cult TV series "Twin Peaks": 2 wds. |
| 51% | JOHNLENNON | 10 | English songwriter who co-founded the Beatles and is known for his song "Imagine": 2 wds. |
| 50% | GRETATHUNBERG | 13 | Young Swedish environmental activist who is known for urging action on global warming and was nominated for the 2019 Nobel Peace Prize: 2 wds. |
| 50% | SOPHIECRUZ | 10 | Young American activist who is known for ensuring continuance of the DAPA program and was featured in the short "Free Like the Birds": 2 wds. |
| 49% | MELALLEN | 8 | Sportscaster for the Yankees who was known for his line "How about that?!": 2 wds. |
| 49% | PATRICKREED | 11 | American pro golfer who is best known for being the winner of the 2014 WGC-Cadillac Championship: 2 wds. |
| 49% | HENRYCAVILL | 11 | Actor known for playing a DC superhero who will be seen in the new "Mission: Impossible" film: 2 wds. |
| 48% | WALTERPAYTON | 12 | Former NFL player for the Chicago Bears, known as "Sweetness," who is considered one of the greatest RBs ever: 2 wds. |
| 47% | JENNER | 6 | Scientist who discovered the vaccine for smallpox |
| 47% | JFKJR | 5 | Nickname for the presidential son who was also known as "John-John" (2 wds.) |
| 46% | MARIECURIE | 10 | Scientist who was the first female professor at the University of Paris: 2 wds. |
| 46% | MOANINGMYRTLE | 13 | Ghost from the "Harry Potter" series who is known for her constant wailing in the lavatories: 2 wds. |
| 46% | MOTHERTERESA | 12 | Canonized nun who is known for her work in India and has a "family" name: 2 wds. |
| 45% | SHERLOCKHOLMES | 14 | Detective portrayed by Robert Downey Jr., who is known for his unmatched observation and deductive skills: 2 wds. |
| 45% | HARRYSTYLES | 11 | Member of the boy band One Direction who is known for his single "Sign of the Times": 2 wds. |
| 44% | ZAYNMALIK | 9 | Former member of the boy band One Direction who is known for his lead single "Pillowtalk": 2 wds. |
| 44% | CHUCKBERRY | 10 | American songwriter who was one of the pioneers of Rock and Roll and was known for his song "Johnny B. Goode": 2 wds. |
| 44% | PEANUTGALLERY | 13 | Group of kids who were the live audience for 18-Across: 2 wds. |
| 43% | PAULMCCARTNEY | 13 | Singer and bass guitarist for the Beatles who was knighted in 1997: 2 wds. |
| 43% | DADDY | 5 | *___ Yankee, Puerto Rican rapper who is known for the song "Despacito" |
| 42% | JAREDLETO | 9 | "Dallas Buyers Club" actor who is the lead vocalist for Thirty Seconds to Mars: 2 wds. |
| 42% | DAVEGROHL | 9 | American musician who was the drummer for Nirvana and lead vocalist of Foo Fighters: 2 wds. |
| 42% | JANETWEISS | 10 | American musician who was the drummer for bands like Sleater-Kinney and Wild Flag: 2 wds. |
| 42% | MARCOPOLO | 9 | Venetian explorer, who is known to be the first to have detailed accounts of travel to, and about China: 2 wds. |
| 42% | SEANCONNERY | 11 | Scottish actor best known for his role as James Bond, who was knighted in 2000: 2 wds. |
| 42% | JOSHALLEN | 9 | Buffalo Bills quarterback who was the AP Most Valuable Player for the 2024-2025 season: 2 wds. |
| 42% | ROBREINER | 9 | Director of 33-Across who will write a foreword for the book by 15-Across: 2 wds. |