| 100% | HYDE | 4 | Evil title character described by the narrator Gabriel John Utterson |
| 34% | MOANA | 5 | Disney title character aided by the demigod Maui |
| 33% | ARCHIERICE | 10 | Title character in 1957 John Osborne stage play The Entertainer |
| 32% | APERSONSAPERSON | 15 | Tautology spoken by the title character in 11-Down |
| 32% | TSGARP | 6 | John Irving title character played by Robin Williams |
| 31% | ALF | 3 | 1980s sitcom title character who also went by the name Gordon Shumway |
| 30% | AMYDORRIT | 9 | Title character of an 1857 novel by Charles Dickens born and raised in the Marshalsea debtors' prison |
| 29% | TORTILLAFLAT | 12 | 1935 novel by John Steinbeck featuring the character Big Joe Portagee |
| 29% | INSIDEJOB | 9 | Betrayal of trust, hinted at by the circled letters, which form an apt John le Carré title |
| 28% | UNCLEBUCK | 9 | John Candy plays the title character in this film |
| 28% | HARLOWE | 7 | Clarissa —, title character of a 1748 epistolary novel by Samuel Richardson subtitled the History of a Young Lady |
| 28% | SUPERFLY | 8 | 1972 movie title theme describing the main character, Youngblood Priest |
| 28% | SIR | 3 | Title bestowed on Elton John by the Queen |
| 28% | APE | 3 | Animal described by the adjective "simian" |
| 27% | TSGARP | 6 | John Irving character played on the big screen by Robin Williams |
| 27% | BEAR | 4 | Large animal described by the adjective "ursine" |
| 27% | RED | 3 | & 19D The —, 1937 volume of four stories by John Steinbeck whose central character is Jody Tiflin |
| 27% | KANE | 4 | Title character inspired by Hearst |
| 27% | JIMHALPERT | 10 | A character from "The Office" played by John Krasinski, who eventually marries the receptionist Pam: 2 wds |
| 27% | EVE | 3 | Title character played by Sandra Oh |
| 26% | RAYA | 4 | Title character voiced by Kelly Marie Tran |
| 26% | IAN | 3 | Title character of the BBC drama ''Bondmaker'' |
| 26% | ZHIVAGO | 7 | Title character of the 1958 Nobel novel |
| 26% | WANDA | 5 | Title character in a 1988 John Cleese film |
| 26% | OWN | 3 | Title character in a 1988 John Cleese film |
| 26% | RWANDA | 6 | Title character in a classic John Cleese comedy |
| 26% | LOLITA | 6 | Title character of a controversial book by Nabokov |
| 26% | ERIK | 4 | Title character of "The Phantom of the Opera" |
| 26% | SAURON | 6 | Title character of "The Lord of the Rings" |