| 100% | GRIN | 4 | Expression that seems like it would be the opposite of 5-Across? |
| 46% | WIIPLAY | 7 | Nintendo party game (which sounds like it could be the opposite of 1-Across?) |
| 40% | LIGHT | 5 | It can be the opposite of either dark or heavy |
| 40% | OUI | 3 | French word that is the opposite of 14-Across |
| 38% | SEP | 3 | Mo. that seems like it should be seventh |
| 38% | WTF | 3 | Expression of shock that would be vulgar if it wasn't abbreviated |
| 38% | ZETA | 4 | Greek letter that seems like it should be last |
| 37% | NNE | 3 | Direction that is the opposite of SSW |
| 37% | YEAS | 4 | Votes that are the opposite of nays |
| 37% | ALKALINE | 8 | Batteries that are the opposite of acidic |
| 37% | ANTONYM | 7 | Word that is the opposite of another |
| 37% | PRE | 3 | Prefix that is the opposite of "post" |
| 37% | ASANA | 5 | Yoga position like the ones at 9a and 15d that you will encounter during a day of practicing yoga |
| 37% | WHEW | 4 | Word that corresponds to the emoji with a grinning face, beads of sweat and seems to be wiping its brow |
| 36% | INVERSE | 7 | The opposite sounds like it is written as a poem? |
| 36% | NAYS | 4 | Negative votes that are the opposite of yeas |
| 36% | ACIDS | 5 | Caustic substances that are the opposites of bases |
| 36% | UNO | 3 | Card game that looks like the opposite of 4-Across? |
| 36% | NON | 3 | French word that is the opposite of 2-Down |
| 35% | COCOCHANEL | 10 | French fashion designer and namesake of the brand that was founded in 1909 and is known for its perfume No. 5: 2 wds. |
| 35% | TURNRED | 7 | What the focus of a 125-Across will do at its climax |
| 35% | JERUSALEM | 9 | It would be "a crown of glory in the hand of the Lord," to Isaiah |
| 35% | FLU | 3 | Bug that sounds like it was in the air? |
| 35% | AORB | 4 | "Which of the two will it be?" |
| 35% | ODD | 3 | Like 3, 5, and 7 (and the opposite of 50-Across) |
| 35% | OPAL | 4 | Birthstone whose first letter is the same as that of its month |
| 34% | FRAME | 5 | Make it seem like someone else is the baddie, say |
| 34% | HORSEMEN | 8 | It's said four of these will bring the apocalypse |
| 34% | SPEND | 5 | Be the opposite of 4-Down |
| 34% | EYE | 3 | With 5-Across, word that looks like it would sound similarly but doesn't |