| 100% | WARPSPEED | 9 | Faster-than-light rate of travel, on "Star Trek": 2 wds. |
| 42% | JERRYOCONNELL | 13 | "Star Trek: Lower Decks" voice actor who is one of "Your Hosts" on "The Real Love Boat" (2 wds.) |
| 42% | REBECCAROMIJN | 13 | "Star Trek: Strange New Worlds" actress who is one of "Your Hosts" on "The Real Love Boat" (2 wds.) |
| 41% | BEAMUP | 6 | Transport back to the Enterprise, on "Star Trek": 2 wds. |
| 40% | INTOTHEWILD | 11 | 2007 American biographical survival film based on the travels of Christopher McCandless across North America, starring Emile Hirsch: 3 wds. |
| 39% | ZACHARYQUINTO | 13 | Portrayer of Spock in "Star Trek Beyond": 2 wds. |
| 39% | SIMONPEGG | 9 | Portrayer of Scotty in "Star Trek Beyond": 2 wds. |
| 39% | SOUND | 5 | Light travels faster than ___ |
| 39% | WILLIAMSHATNER | 14 | "Star Trek" star who played a murderous actor on "Columbo": 2 wds. |
| 38% | KATEMULGREW | 11 | Actress who played Captain Kathryn Janeway on "Star Trek: Voyager": 2 wds. |
| 38% | WILWHEATON | 10 | "Star Trek: The Next Generation" actor who guest stars as himself on "The Big Bang Theory" (2 wds.) |
| 38% | LIONELTRAINS | 12 | Classic toys that travel on tracks: 2 wds. |
| 38% | TACHYON | 7 | Particle that travels faster than light |
| 37% | AVERYBROOKS | 11 | Actor who played Captain Benjamin Sisko on "Star Trek: Deep Space Nine": 2 wds. |
| 37% | ARAY | 4 | "Quicker than ___ of light" (Madonna lyrics): 2 wds. |
| 37% | KALEYCUOCO | 10 | Portrayer of Penny on 42-Across: 2 wds. |
| 36% | HYPERDRIVE | 10 | Way to travel faster than light, in sci-fi |
| 36% | TACHYON | 7 | Hypothetical particle that travels faster than light |
| 36% | JOSHBROLIN | 10 | Star of "Labor Day": 2 wds. |
| 36% | BILLMURRAY | 10 | Star of "Groundhog Day": 2 wds. |
| 36% | HUGHLAURIE | 10 | Star of "House": 2 wds. |
| 36% | SPEED | 5 | Rate of travel |
| 35% | NOELWELLS | 9 | "Master of None" actress who voices ensign D'Vana Tendi on "Star Trek: Lower Decks": 2 wds. |
| 35% | LAVALAMP | 8 | Psychedelic light source of the 1960s: 2 wds. |
| 35% | LAVALAMP | 8 | Trippy light fixture of the 1960s: 2 wds. |
| 35% | JLO | 3 | "Shades of Blue" star, familiarly: 2 wds. |
| 35% | CAROLKANE | 9 | "The Princess Bride" actress who plays Pelia on "Star Trek: Strange New Worlds": 2 wds. |
| 35% | LEGENDS | 7 | "___ of Tomorrow," DC superhero TV series on time travel starring Arthur Darvill |
| 35% | ONEHUNDRED | 10 | Number of candles on a cake for 18-Across: 2 wds. |
| 35% | BARCODES | 8 | Scannable sets of lines on product packaging: 2 wds. |